摘要
目的探究药物涂层球囊在急性心肌梗死患者直接经皮冠状动脉介入治疗中短期的有效性及安全性。方法纳入2018年1月—2019年6月于郑州大学第一附属医院使用药物涂层球囊行直接经皮冠状动脉介入治疗的急性心肌梗死患者66例,回顾性分析患者的基线资料、介入治疗情况和即刻疗效,观察术后半年内的主要不良心血管事件。结果66例急性心肌梗死患者,年龄(56.2±12.1)岁,男性51例(77.3%),包括ST段抬高型心肌梗死患者29例(43.9%)。63例(95.5%)顺利完成手术,3例(4.5%)行补救性支架置入术。62例患者完成半年的随访,MACE发生率为6.5%,其中3例再狭窄行靶病变血运重建(2例临床症状驱动,1例无症状再狭窄),1例心源性死亡,无靶血管再梗死事件发生。结论药物涂层球囊在急性心肌梗死患者直接经皮冠状动脉介入的治疗中短期内安全、有效。
Objective To investigate the short-term efficacy and safety of drug coated balloon in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention.Methods A retrospective study on 66 patients with acute myocardial infarction who underwent drug coated balloon strategy in primary percutaneous coronary intervention at the First Affiliated Hospital of Zhengzhou University from January 2018 to June 2019 was conducted.The baseline data and procedure characteristics of the patients were analyzed retrospectively.The main adverse cardiovascular events within half a year after operation were followed up.Results There were 66 patients(77.3%male,mean age 56.2±12.1)with acute myocardial infarction,including 29 patients(43.9%)with ST segment elevation myocardial infarction.63 patients(95.5%)were performed the operation successfully and 3 patients(4.5%)were underwent bail-out stenting.62 patients completed the six-month follow-up,and the incidence of MACE was 6.5%,including three patients of restenosis with target lesion revascularization(two clinically symptom-driven,one asymptomatic restenosis)and one patient of cardiac death.There was no target vessel reinfarction events.Conclusion Drug coated balloon angioplasty is safe and effective in primary percutaneous coronary intervention for the patients with acute myocardial infarction in the short term.
作者
胡振振
孟哲
王丹
姬广招
陆明辉
齐莹
陶海龙
HU Zhen-zhen;MENG Zhe;WNAG Dan;JI Guang-zhao;LU Ming-hui;QI Ying;TAO Hai-long(Department of Cardiology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处
《医药论坛杂志》
2020年第7期68-72,共5页
Journal of Medical Forum
关键词
急性心肌梗死
药物涂层球囊
直接经皮冠状动脉介入治疗
短期疗效
Acute myocardial infarction
Drug coated balloon
Primary percutaneous coronary intervention
Short-term effect
