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假基因在子宫内膜癌中的研究进展

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摘要 假基因是一段具有与功能基因相似的DNA序列,但由于存在许多突变以致失去了原有的功能。长期以来假基因被认为是无功能的DNA序列,但最近的研究发现,假基因具有广泛的生物学功能,可参与体内细胞分化、炎症和凋亡等重要生命活动过程,其中在子宫内膜癌中,它可以通过调控相关基因影响肿瘤的发生、发展、侵袭及转移。本文通过综述假基因的分类进化、识别,与子宫内膜癌的相关性及其在子宫内膜癌中的作用机制,探讨假基因与子宫内膜癌关系的研究进展。
出处 《癌症进展》 2020年第13期1312-1314,1366,共4页 Oncology Progress
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