摘要
目的探讨药物治疗失败的卡梅现象(KMP)的临床特点及手术效果。方法抽取2012年1月至2017年12月于河南省人民医院经药物治疗失败的KMP患儿47例,男26例,女21例,年龄1~11个月,行单纯血管瘤切除术或血管瘤切除+原位植皮术。分析其临床表现、术中及术后情况。结果47例患儿年龄较小,血管瘤发展至KMP时间为0~11个月,瘤体位置深且面积大。41例行单纯血管瘤切除术,行血管瘤切除+原位植皮术6例。手术时间35~260 min,出血量20~380 ml,血小板计数术后1~9 d恢复正常、2~60 d出现峰值,住院时间14~72 d,随访24~78个月未见复发、功能障碍者。结论KMP进展时间短,药物保守治疗失败者手术可获得较好的治疗效果。
Objective To investigate features and surgical results of Kasabach-Merritt phenomenon(KMP)with failed drug therapy.Methods Forty-seven children with KMP who failed drug treatment in Henan Provincial People’s Hospital from January 2012 to December 2017,26 males and 21 females,aged 1 to 11 months,underwent simple hemangiomas or hemangiomas resection+skin graft in situ.The clinical manifestations,intraoperative and postoperative conditions of them were analyzed.Results Forty-seven children were younger.The time from hemangioma to KMP was 0 to 11 months.The tumor was deep and large.Forty-one patients underwent simple hemangiomas resection and 6 patients underwent hemangioma resection and skin graft.The operation time was 35 to 260 minutes,and the bleeding volume was 20 to 380 ml.The platelet count returned to normal on the 1 to 9 days after surgery,the peak appeared at 2 to 60 days,and the hospitalization time was 14 to 72 days.No recurrence or dysfunction patients was found after follow-up for 24 to 78 months.Conclusions The progression time of KMP is short,and the patients who fail in conservative treatment of medicine can get better treatment effect.
作者
王彦林
董长宪
郭晓楠
刘大看
肖莉
左松
任腾飞
Wang Yanlin;Dong Changxian;Guo Xiaonan;Liu Dakan;Xiao Li;Zuo Song;Ren Tengfei(Department of Hemangioma Surgery,Henan Provincial People’s Hospital,Zhengzhou 450000,China)
出处
《中国实用医刊》
2020年第8期1-4,共4页
Chinese Journal of Practical Medicine
基金
2019国家自然科学基金青年科学基金项目(81800991)。
关键词
卡梅现象
血管瘤
植皮
Kasabach-Merritt phenomenon
Hemangioma
Skin grafting
