摘要
目的探讨脑膜脑膨出的临床病理特点,以提高对本病的认识。方法回顾性分析2008年5月至2018年1月在首都医科大学附属北京天坛医院和2010年6月至2018年10月在首都医科大学附属北京同仁医院接受脑膜脑膨出手术治疗的患者各15例(共30例)的病例资料。结果 30例脑膜脑膨出患者平均年龄为(21.8±23.3)岁,男:女为1.73:1。先天性脑膜脑膨出占53.33%,自发性脑膜脑膨出占36.67%,外伤性脑膜脑膨出占10%。先天性脑膜脑膨出平均年龄(3.3±5.7)岁,男:女为1.6:1,顶枕部最常见(81.25%)。自发性脑膜脑膨出平均年龄(46.8±11.3)岁,男:女为1.75:1,蝶窦外侧壁最常见(72.73%)。顶枕额部可见皮肤组织、脑组织及脑膜组织,脑组织为成熟的神经胶质,其他部位无皮肤组织。结论脑膜脑膨出是一类以脑膜及脑组织经缺损部位向外膨出为特征的疾病,目前临床病理报道较少,对怀疑脑膜脑膨出者,不可穿刺、活检或盲目切除,必须进行影像学检查明确肿物来源。
Objective To investigate the clinicopathological features of meningoencephalocele(encephalocele) to improve the cognition of the disease. Method 30 patients with congenital, spontaneous and traumatic encephalocele were enrolled in this retrospective study to investigate the clinical and morphological data. Result The mean age was(21.8±23.3) years old, and the ratio of male:female was 1.73:1. Congenital accounted for 53.33%, spontaneous accounted for 36.67% and traumatic accounted for 10%. Congenital encephalocele, the mean age was(3.3±5.7) years old, the ratio of male:female patients was 1.6:1, parietal and occipital region accounted for 81.25%. Spontaneous encephalocele, mean age was(46.8±11.3) years old, the ratio of male:female patients was 1.75:1, the lateral wall of the sphenoid sinus was common(72.73%). Histological features, skin, brain tissue and meningeal tissue were seen in parietal, occipital and frontal site, but without skin in other sites. The brain tissue was mature glial. Conclusion Encephalocele was a kind of disease characterized by bulging out of meninges and brain tissues through the defect. There were few reports in pathology at present.
作者
李雪
武迎
张红
李铭孝
朴颖实
董格红
刘红刚
Li Xue;Wu Ying;Zhang Hong;Li Mingxiao;Piao Yingshi;Dong Gehong;Liu Honggang(Department of Pathology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;Department of Pathology,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;Beijing Key Laboratory of Head and Neck Molecular Diagnostic Pathology,Capital Medical University,Beijing 100730,China;Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)
出处
《中国医刊》
CAS
2020年第8期885-888,共4页
Chinese Journal of Medicine
基金
北京市医院管理局临床医学发展专项“扬帆”计划(ZYLX201814)。
关键词
脑膜
脑膨出
临床
病理
分析
Meninges
Encephalocele
Clinical
Pathological
Analysis
