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左氧氟沙星片联合盐酸乙胺丁醇片治疗肺结核的疗效及对T淋巴细胞亚群的影响 被引量:3

Efficacy of Levofloxacin Tablets Combined with Ethambutol Hydrochloride Tablets in the Treatment of Tuberculosis and Its Effect on T Lymphocyte Subsets
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摘要 目的:研究左氧氟沙星片与盐酸乙胺丁醇片联合治疗肺结核的效果以及对患者T淋巴细胞亚群的影响。方法:选取在某院确诊为肺结核并接受治疗的患者80例,采用随机抽签的方法,将80例患者均分为对照组和观察组各40例。对照组患者通过常规抗结核分枝杆菌方案进行治疗,观察组患者在对照组患者的基础上通过左氧氟沙星片与盐酸乙胺丁醇片进行联合治疗,对比两组患者的治疗效果及相关指标。结果:观察组患者治疗的总有效率为90%,显著高于对照组患者的70%(P<0.05);两组患者治疗后观察组患者的改善情况显著优于对照组患者(P<0.05)。结论:左氧氟沙星片与盐酸乙胺丁醇片联合治疗肺结核有更好的治疗效果,对于患者T淋巴细胞亚群情况的改善也有着更好的效果。 Objective:To study the effect of levofloxacin tablets combined with ethambutol hydrochloride tablets on tuberculosis and its effect on T lymphocyte subsets.Methods:Eighty patients with tuberculosis diagnosed and treated in a hospital were selected and divided into control group and observation group by using random sampling,with 40 cases in each group.The patients in the control group were treated with the conventional anti-tuberculosis mycobacterial regimen.The patients in the observation group were treated with levofloxacin tablets and ethambutol hydrochloride tablets on the basis of the control group,and the therapeutic effects and related indexes of the two groups were compared.Results:The total effective rate of the treatment group was 90%,which was significantly higher than that of the control group(70%)(P<0.05).The improvement of the observation group was significantly better than that of the control group(P<0.05).Conclusion:Levofloxacin tablets combined with ethambutol hydrochloride tablets has a better therapeutic effect on tuberculosis,and has a better effect on the improvement of T lymphocyte subsets.
作者 苏玉欣 Su Yuxin(Department of Pharmacy,Henan Provincial People's Hospital,Huazhong Fuwai Hospital,Huazhong Fuwai Hospital of Zhengzhou University,Zhengzhou 450000)
出处 《数理医药学杂志》 2020年第8期1196-1197,共2页 Journal of Mathematical Medicine
关键词 左氧氟沙星片 盐酸乙胺丁醇片 疗效 T淋巴细胞亚群 levofloxacin tablets ethambutol hydrochloride tablets efficacy T lymphocyte subsets
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