摘要
目的探讨右美托咪定在小儿麻醉中的应用效果。方法选取116例进行全麻手术的患儿作为研究对象,将其分为右美托咪定组与丙泊酚组,各58例。对比2组患儿用药后的血流动力学、术后疼痛程度、躁动量化评分和手术效果。结果2组麻醉时间、拔管时间及苏醒时间相比,差异无统计学意义(P>0.05);右美托咪定组的躁动评分、疼痛评分以及躁动发生率均显著低于丙泊酚组(P<0.05);2组恶心、呕吐发生率相比,差异无统计学意义(P>0.05);右美托咪定组T1时点的平均动脉压低于丙泊酚组,T1、T3时点的心率低于丙泊酚组,差异均有统计学意义(P<0.05)。结论全麻手术患儿采用右美托咪定维持麻醉,血流动力学稳定,躁动发生率低,疼痛感较轻。
Objective To analyze the effect of dexmedetomidine in pediatric anesthesia.Methods A total of 116 children who underwent general anesthesia in our hospital were selected and divided into dexmedetomidine group(n=58)and propofol group(n=58).Hemodynamics,postoperative pain,agitation quantification score,surgical effect were compared between the two groups.Results There were no differences in anesthesia time,extubation time,and wake-up time between the two groups(P>0.05).Compared with the propofol group,the dexmedetomidine group had lower rate of agitation,pain score,and incidence of agitation(P<0.05);there was no difference in the incidence of nausea and vomiting between the two groups(P>0.05);the mean arterial pressure at time point of T1 in the dexmedetomidine group was lower(P<0.05),and heart rates at time points of T1 and T3 were lower than those in the propofol group(P<0.05).Conclusion Maintained anesthesia of dexmedetomidine for children undergoing general anesthesia has stable hemodynamics,lower incidence of agitation,and less pain.
作者
郑凌
朱崇军
ZHENG Ling;ZHU Chongjun(Department of Anesthesiology,Xi′an City Fourth Hospital,Xi′an,Shaanxi,710000)
出处
《实用临床医药杂志》
CAS
2020年第11期62-64,67,共4页
Journal of Clinical Medicine in Practice
关键词
全身麻醉
右美托咪定
血流动力学
苏醒期躁动
疼痛程度
general anesthesia
dexmedetomidine
hemodynamics
agitation during awaking
pain degree
