摘要
目的分析视神经脊髓炎(neuromyelitis optica,NMO)MRI影像学特点。方法回顾分析2009年2月至2018年9月开封市中心医院收治的视神经脊髓炎病人30例,采用1.5T MR扫描仪对病人行头颅及脊髓核磁共振(MRI)检查,分析病人脑部病灶、脊髓病灶及视神经病灶的分布特点。结果 30例NMO病人女性多于男性,约9∶1;30例病人的MRI检查中出现脑部病变25例。病变主要位于水通道蛋白质4(AQP-4)高表达区及大脑白质区等处,病灶多呈斑点、斑片状,大部分对称分布,部分病灶融合成片状。脊髓MRI异常24例,主要累及颈髓、胸髓,表现为多于3个椎体节段的连续性、对称性病灶。视神经MRl异常11例,主要累及视神经后段,常双侧受累,病灶节段长度大部分大于1/2视神经。颅脑增强表现云雾样及薄线样强化,脊髓病灶呈点状、小斑片状、线条状及环形均匀或不均匀强化,视神经呈轻度强化。结论 MRI检查为视神经脊髓炎诊断提供了可靠依据。
Objective neuritis treated in Kaifeng Central Hospital from February 2009 to September 2018 were retrospectively analyzed and performed with a 1.5 T MR scanner to examine the head and spinal cord magnetic resonance imaging(MRI).The patient’s brain lesions,spinal cord lesions and optic nerve lesions distribution characteristics were analyzed.Results There were more women than men in30 cases of NMO,about 9:1.In 30 patients,25 cases of brain lesions occurred in MRI examination.The lesions were mainly located in the high expression area of AQP-4 and the white matter area of the brain,and the lesions were mostly spotted and patchy,most of them were symmetrical,and some of the lesions fused into patches.MRI abnormalities in the spinal cord were 24 cases,mainly involving the cervical medulla and thoracic pulp,and showed the continuity and symmetrical long lesions of more than 3 vertebrae segments.11 cases of optic nerve MRI abnormalities,mainly involved in the posterior segment of the optic nerve,often bilateral involvement,the length of the lesion segment is greater than 1/2 optic nerve.Craniocerebral enhancement showed cloudy sample and thin line-like enhancement,spinal cord lesions showed point,small patches,lines and annular uniform or uneven enhancement,the optic nerve showed mild enhancement.Conclusion MRI examination provides a reliable basis for diagnosis of optic myelitis.
作者
张倩倩
张体华
周玫娟
范娜
钱伟军
ZHANG Qianqian;ZHANG Tihua;ZHOU Meijuan;FAN Na;QIAN Weijun(Author Affiliations:1Department Of Imaging,Kaifeng Central Hospital,Kaifeng,Henan 475000,China;Shangqiu Medical College,Shangqiu,Henan,476000,China)
出处
《安徽医药》
CAS
2020年第8期1534-1536,I0002,共4页
Anhui Medical and Pharmaceutical Journal
基金
河南省高等教育教学改革研究与实践项目(2017SJGL649)。
