摘要
对《化妆品安全技术规范》(2015年版)中有关米诺地尔含量测定进行不确定度的评估。参考JJF1059.1-2012《测量不确定度评定与表示》,建立数学模型,考察了分析过程中引入不确定度的主要因素,计算出合成标准不确定度和扩展不确定度。结果表明,标准品称量、标准系列溶液的配制、进样精密度、样品回收率对样品的相对不确定度贡献较大。
The uncertainty of Minoxidil content determination in "Cosmetic Safety Technical Specification" (2015 Edition) was evaluated.Referring to JJF1059.1-2012 "Evaluation and Expression of Uncertainty in Measurement",a mathematical model was established,the main factors of introducing uncertainty in the analysis process were investigated,and the combined standard uncertainty and expanded uncertainty were calculated.The results show that the weighing of standard substance,the preparation of standard series solution,the precision of sample injection and the recovery rate of sample contribute greatly to the relative uncertainty of sample.
作者
付金凤
朱晓雯
Fu Jinfeng;Zhu Xiaowen(Changzhou Food and Drug Supervision and Inspection Center,Jiangsu,213001)
出处
《当代化工研究》
2020年第14期156-157,共2页
Modern Chemical Research
关键词
液相色谱-串联质谱法
化妆品
不确定度
liquid chromatography-tandem mass spectrometry
cosmetics
uncertainty
