摘要
目的探讨磁共振三维准连续动脉自旋标记(3D-PCASL)扫描技术在偏头痛患者发作期中的应用价值。方法收集2019-01-05在昆明市延安医院就诊的20例偏头痛患者及20例健康志愿者,采用磁共振三维准连续动脉自旋标记扫描技术进行脑灌注扫描,病例组分别在发作期和间歇期扫描,健康组在平息状态下扫描,测量2组脑血流量(CBF)并进行比较。结果实验组疼痛发作期患侧颞叶CBF值[(53.14±3) mL/(100 g·min)]低于健侧[(54.99±3.18) mL/(100 g·min),t=-2.125,P<0.05],病患组颞叶CBF灌注值[(53.14±3) mL/(100 g·min)]较对应健康对照组区域[(55.99±2.44)mL/(100 g·min),t=-3.308,P<0.05]减低。病例组在间歇期CBF值未见明显变化。结论三维准连续动脉自旋标记扫描技术能够监测健侧全脑血流灌注情况,对偏头痛患者进行量化分析,为临床医生提供客观的诊疗依据。
Objective To explore magnetic resonance arterial spin labeling(3 D-PCASL) scanning technology application value in patients with migraine episodes.Methods Patients from January 2019 to May 2019 in our hospital were collected and 20 cases of healthy volunteers,20 patients with migraine by magnetic resonance(MR) arterial spin labeling cerebral perfusion scanning technology,disease group in episodes and intermittent period scanning,health under the state of calm scanning,measuring both groups the value of the cerebral blood flow(CBF) and to compare the difference.Results The pain episodes of lateral temporal lobe CBF value[(53.14±3) mL/(100 g·min)]lower than the contralateral[(54.99±3.18)mL/(100 g·min),t=-2.125,(P<0.05)],the patient group of temporal lobe CBF perfusion value[(55.38±3.85)mL/(100 g·min)]CBF value corresponding to the healthy controls area[(55.99±2.44) mL/(100 g·min),t=-3.308,P<0.01].Patient groups in intermittent period CBF value no obvious change.Conclusion Arterial spin labeling to the contralateral whole brain perfusion scanning technology,a quantitative analysis in migraine patients,provides the objective diagnostic basis for the clinical doctors.
作者
马鹏程
万文
王晋
邬刚
彭桂兰
李青芸
董小林
马立柔
MA Pengcheng;WAN Wen;WANG Jin;WU Gang;PENG Guilan;LI Qingyun;DONG Xiaolin;MA Lirou(Kunming Yan’an Hospital,Kunming 650000,China)
出处
《中国实用神经疾病杂志》
2020年第14期1236-1240,共5页
Chinese Journal of Practical Nervous Diseases
基金
云南省教育厅科学研究基金项目(编号:2018JS237)
昆明市卫生科技人才培养项目暨“十百千”工程项目[编号:2018-sw(后备)-12]
昆明市卫生科技人才培养项目暨“内设研究机构”建设项目[编号:2018-sw(后备)-60]
昆明市延安医院院内项目(编号:yyky019-021)。
关键词
动脉自旋标记
偏头痛
磁共振成像
脑血流量
全脑灌注
Arterial spin labeling
Migraine
Magnetic resonance imaging
Cerebral blood flow
Whole brain perfusion
