摘要
目的分析该院住院患者临床常见细菌分布及抗菌药物耐药性变迁,为临床合理应用抗菌药物提供依据。方法收集2012-2016年该院住院患者送检样品分离到的细菌,回顾性分析其来源、分布规律、耐药情况。结果该院5年间住院患者临床分离菌中,革兰阴性杆菌高于革兰阳性球菌,从阳性标本来源分析呼吸道标本居第一位,其次为血液,该院临床分离的常见菌主要包括大肠埃希菌、肺炎克雷伯菌、鲍曼不动杆菌、铜绿假单胞菌、金黄色葡萄球菌。5年间多重耐药菌出现较大幅度的上升。结论该院住院患者致病菌以革兰阴性杆菌为主,医院细菌总体耐药情况在2016年有改善,但多重耐药菌仍逐年增加。
Objective To analyze the features of distribution of bacteria and their resistance against antimicrobial agents of hospitalized patients in the hospital,and ventured to seek suitable solutions for the problems.Methods Bacteria were isolated from the inpatients in the hospital from 2012 to 2016,and a retrospective analysis of their sources,distribution and drug resistance to various antibiotics was made.Results The proportion of Gram-negative bacilli was higher than that of Gram-positive cocci in the clinical bacteria isolated of hospitalized patients in this five years.In the analysis of the source of positive specimens,respiratory tract ranked first followed by serum.Common bacteria isolated in the hospital mainly included Escherichia coli,Klebsiellapneumoniae,Acinetobacterbaumanii,Pseudomonas aeruginosa and Staphylococcus epidermidis.Over the 5 years,multidrug-resistant bacteria appeared on a larger scale.Conclusion Gram-negative bacteria are the main pathogens in hospitalized patients.The overall drug resistance condition of hospital bacteria has improved in 2016 but still at a high level,multi drug resistant bacteria are still increasing year by year.
作者
何禄娟
刘胜岗
石国民
杨红忠
HE Lujuan;LIU Shenggang;SHI Guoming;YANG Hongzhong(Respiratory Diagnosis and Treatment Center,the Center Hospital of Changsha,Changsha,Hunan 41000,China;Department of Clinical Laboratory,the Center Hospital of Changsha,Changsha,Hunan 41000,China)
出处
《检验医学与临床》
CAS
2020年第S01期37-41,共5页
Laboratory Medicine and Clinic
关键词
感染菌群
耐药性
药敏
infection bacteria
resistance distribution
drug sensitivity
