摘要
目的探讨PCI术后应用三联抗凝对冠心病合并房颤患者CRP、 PLT、 Fg以及D-D水平的影响。方法 120例接受PCI手术的冠心病合并房颤患者随机分为两组各60例。PCI术后,对照组行二联抗凝治疗,观察组行三联抗凝治疗。比较两组的实验室指标水平,以及不良事件发生情况。结果治疗6个月后,两组的CRP、 PLT、 Fg以及D-D水平均显著下降,且观察组的各项指标均显著低于对照组(P <0.05)。观察组的心血管事件及下肢DVT发生率显著低于对照组(P <0.05)。两组的出血事件发生率比较,差异无统计学意义(P>0.05)。结论 PCI术后应用三联抗凝可改善冠心病合并房颤患者的CRP、 PLT、 Fg、 D-D水平,促进血液微循环,降低心血管事件及下肢DVT发生率。
Objective To explore the effects of application of triple anticoagulation after PCI on CRP,PLT,Fg and D-D levels of patients with coronary heart disease(CHD)complicated with atrial fibrillation(AF).Methods 120 patients with CHD complicated with AF who underwent PCI were randomly divided into two groups,with 60 cases in each group.After PCI,the control group received double anticoagulation therapy,while the observation group received triple anticoagulation therapy.The levels of laboratory indicators and the incidences of adverse events were compared between the two groups.Results After 6 months of treatment,the levels of CRP,PLT,Fg and D-D in both groups significantly decreased,and the indicators in the observation group were significantly lower than those in the control group(P<0.05).The incidence of cardiovascular events and lower limb DVT in the observation group was significantly lower than that in the control group(P<0.05).No significant difference was found in the incidence of bleeding events between the two groups(P>0.05).Conclusions The application of triple anticoagulation after PCI can improve the CRP,PLT,Fg and D-D levels of patients with CHD complicated with AF,promote blood microcirculation,and reduce the incidence of cardiovascular events and lower limb DVT.
作者
李明
于群
刘影倩
LI Ming;YU Qun;LIU Yingqian(Department of Thoracic Surgery,Zhuhai Fifth People's Hospital,Zhuhai 519055,China;Department of General Surgery,Zhuhai Fifth People's Hospital,Zhuhai 519055,China)
出处
《临床医学工程》
2020年第8期1031-1032,共2页
Clinical Medicine & Engineering
关键词
冠心病
房颤
三联抗凝
PCI
CRP
PLT
FG
D-D
心血管事件
Coronary heart disease
Atrial fibrillation
Triple anticoagulation
PCI
CRP
PLT
Fg
D-D
Cardiovascular events
