摘要
目的分析原发性腹膜后副神经节瘤的临床病理特征及外科治疗情况。方法回顾性分析2015年1月至2018年12月北京大学国际医院腹膜后肿瘤外科收治的24例行手术治疗的原发性腹膜后副神经节瘤患者的临床病理资料及外科治疗情况。结果24例腹膜后副神经节瘤患者中10例术前无症状,14例术前有高血压、头晕、头痛、腹痛、腹部不适等症状。腹盆部增强CT扫描显示肿瘤最大径为3.4~13.0 cm,平均(6.9±2.5)cm,所有肿瘤均分布于腹主动脉、下腔静脉旁。24例患者均接受手术治疗。与术中血压平稳患者相比,术中血压明显波动患者的手术时间更长、术中出血更多、术中输血更多、住院时间更长,差异均有统计学意义(均P<0.05)。术后随访16~52个月,1例患者因肿瘤复发死亡,其余患者均存活,并且未见肿瘤复发。结论外科手术切除是腹膜后副神经节瘤的主要治疗手段;术前充分地评估及准备可能有助于降低患者围手术期风险。
Objective To evaluate the clinicopathological features of primary retroperitoneal paragangliomas.Methods Data of 24 patients with retroperitoneal paragangliomas who underwent surgical treatment in our hospital from Jan 2015 to Dec 2018 was collected and analyzed.Results Hypertension,abdominal pain/discomfort and headache were the most common complaints while 10 patients were asymptomatic and were diagnosed accidently in routine body examination.Tumor size ranged from 3.4-13.0 cm(6.9±2.5)cm,and all the tumors were located in the vicinity of abdominal aorta and inferior vena cava.All the patients received surgical treatment.Intraoperative blood pressure fluctuations were significantly correlated with prolonged operation time,more blood loss,more blood transfusion and prolonged length of stay(all P<0.05).The median follow-up time was 29 months and 1 patient died from tumor recurrence and progression.The other patients have had a tumor free survival.Conclusions Surgical resection was the principal treatment of primary paraganglioma.Preoperative assessment was very important for perioperative safety.
作者
高海成
肖萌萌
李文杰
张小龙
陈骏
苗成利
罗成华
Gao Haicheng;Xiao Mengmeng;Li Wenjie;Zhang Xiaolong;Chen Jun;Miao Chengli;Luo Chenghua(Department of Retroperitoneal Tumors,Peking University International Hospital,Beijing 102206,China;Department of Pathology,Peking University International Hospital,Beijing 102206,China)
出处
《中华普通外科杂志》
CSCD
北大核心
2020年第6期446-448,共3页
Chinese Journal of General Surgery
基金
北京市科委"首都临床特色应用研究"专项(Z171100001017095)。
关键词
副神经节瘤
腹膜后肿瘤
病理学
临床
外科手术
Paraganglioma
Retroperitoneal tumors
Pathology
clinical
Surgical procedures
operative
