摘要
目的:评价"调经促孕十三针"针法治疗卵巢储备功能下降(DOR)的临床疗效及对卵巢储备功能的影响。方法:32例DOR患者采用"调经促孕十三针"针法治疗。穴组1:百会、神庭、本神、中脘、天枢、关元、子宫、大赫、足三里、三阴交、太冲;穴组2:百会、肾俞、次髎。穴组1与穴组2轮流交替使用,首次取穴组1。每次留针30 min,隔1?2日1次,每周3次,36次(3个月)为一疗程,可持续治疗至患者妊娠或患者放弃针刺治疗,月经期间针刺不间断。比较患者治疗前后改良Kupperman量表评分及血清性激素、抗苗勒管激素(AMH)水平、卵巢血流收缩期峰值流速(PSV)及阻力指数(RI)和窦卵泡计数(AFC)的变化,并观察临床有效率、妊娠率。结果:治疗后改良Kupperman量表总评分较治疗前降低(P<0.05);总有效率为90.6%(29/32),妊娠率为15.6%(5/32)。治疗后卵泡刺激素(FSH)、FSH/黄体生成素(LH)水平较治疗前降低,卵巢PSV较治疗前增高、RI较治疗前减低,AFC较治疗前增加(P<0.05)。结论:"调经促孕十三针"针法可有效提高DOR患者卵巢储备功能。
Objective To evaluate the clinical effect of acupuncture at "thirteen acupoints for regulating menstruation and promoting pregnancy" on diminished ovarian reserve(DOR) and its influence on ovarian reserve function. Methods A total of 32 patients with DOR were treated by acupuncture at "thirteen acupoints for regulating menstruation and promoting pregnancy". Acupoints group 1: Baihui(GV 20), Shenting(GV 24), Benshen(GB 13), Zhongwan(CV 12), Tianshu(ST 25), Guanyuan(CV 4), Zigong(EX-CA 1), Dahe(KI 12), Zusanli(ST 36), Sanyinjiao(SP 6), Taichong(LR 3);acupoints group 2: Baihui(GV 20), Shenshu(BL 23), Ciliao(BL 32). Acupoints group 1 and group 2 were alternately used, and acupoints group 1 was used for the first time. The needles were stayed for 30 min each time, once every 1 or 2 days, 3 times a week, 36 times(3 months) as a course of treatment. The treatment could be continued until the patient was pregnant or the patient given up acupuncture, and the acupuncture was uninterrupted during menstruation. The changes of modified Kupperman scale score, serum sex hormones, anti-müllerian hormones(AMH), ovarian peak systolic velocity(PSV), resistive index(RI) and antral follicle count(AFC) were compared before and after treatment, and the clinical effect and pregnancy rate were observed. Results The total score of modified Kupperman scale after treatment was lower than that before treatment(P<0.05);The total effective rate was 90.6%(29/32) and the pregnancy rate was 15.6%(5/32). After treatment, the levels of follicle stimulating hormone(FSH), FSH/luteinizing hormone(LH) were lower than before treatment, ovarian PSV was higher than before treatment, RI was lower than before treatment, and AFC was more than before treatment(P<0.05). Conclusion Acupuncture at "thirteen acupoints for regulating menstruation and promoting pregnancy" can effectively improve the ovarian reserve function of DOR patients.
作者
杨福霞
杨卓欣
YANG Fu-xia;YANG Zhuo-xin(Department of Acupuncture and Moxibustion,Shenzhen TCM Hospital,Shenzhen 518033,Guangdong Province,China)
出处
《中国针灸》
CAS
CSCD
北大核心
2020年第6期619-622,共4页
Chinese Acupuncture & Moxibustion
基金
广东省名中医传承工作室建设项目:粤中医办函(2017)17号
深圳市医疗卫生“三名工程”中国中医科学院刘保延首席研究员中医针灸临床评价方法创新团队项目:SZSM201612001。
关键词
卵巢储备功能下降
调经促孕十三针
针刺
改良Kupperman量表
diminished ovarian reserve
thirteen acupoints for regulating menstruation and promoting pregnancy
acupuncture
modified Kupperman scale
