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消炎痛栓预防ERCP术后胰腺炎的疗效观察

Observation of Curative Effect of Xiaoyantong Suppository on Prevention of Pancreatitis after ERCP
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摘要 目的分析消炎痛栓对于接受内镜下逆行胰胆管造影术(ERCP)治疗后胰腺炎发生的预防效果。方法以2017年1月-2019年9月62例接受ERCP治疗的胆管疾病患者为对象进行回顾性分析,随机将患者分为观察组与对照组,均有31例患者,其中对照组ERCP术前未使用肛门消炎痛栓,观察组ERCP术前半小时给予肛门消炎痛栓1粒,比较两组ERCP术后胰腺炎发生率、术后腹痛率、淀粉酶水平、住院时间、住院费用。结果观察组术后胰腺炎、腹痛、高淀粉酶血症发生率为3.23%、6.45%、6.45%,均低于对照组19.35%、25.81%、25.81%(χ^2=4.025、4.292、4.492,P<0.05),观察组患者术后6 h、术后24 h血清淀粉酶水平均低于对照组(P<0.05);观察组术后住院时间短于对照组,住院费用少于对照组(P<0.05)。结论对于接受ERCP治疗的患者,术前半小时直肠给药1粒消炎痛栓能够有效减少术后胰腺炎的发生,控制淀粉酶水平升高,减少高淀粉酶血症,减少腹痛的发生,加快患者出院,减低患者经济负担,有良好应用价值。 Objective To analyze the preventive effect of indomethacin on the occurrence of pancreatitis after endoscopic retrograde cholangiopancreatography(ERCP).Methods A retrospective analysis was performed on 62 patients with bile duct disease receiving ERCP from January 2017 to September 2019.The patients were randomly divided into observation group and control group,each with 31 patients,of which ERCP was performed in the control group.Anus indomethacin suppository was not used before,and anal indomethacin suppository was given one capsule half an hour before ERCP in the observation group.The incidence of postoperative pancreatitis,postoperative abdominal pain rate,amylase level,length of hospitalization,and hospitalization cost were compared between the two groups.Results The incidences of postoperative pancreatitis,abdominal pain,and hyperamylase in the observation group were 3.23%,6.45%,and 6.45%,which were lower than those in the control group at 19.35%,25.81%,and 25.81%(χ^2=4.025,4.292,4.492,P<0.05),the serum amylase levels of patients in the observation group at 6 h and 24 h after the operation were lower than those in the control group(P<0.05);the hospital stay in the observation group was shorter than that in the control group,and the hospitalization cost was less than that in the control group(P<0.05).Conclusion For patients receiving ERCP,rectal administration of one indomethacin suppository half an hour before surgery can effectively reduce the incidence of postoperative pancreatitis,control the increase of amylase levels,reduce hyperamylaseemia,reduce the occurrence of abdominal pain,and accelerate discharge of patients reduces the financial burden on patients and has good application value.
作者 钱后福 QIAN Hou-fu(Department of Gastroenterology,Second People's Hospital of Taizhou,Taizhou,Jiangsu Province,225500 China)
出处 《中外医疗》 2020年第13期105-107,共3页 China & Foreign Medical Treatment
关键词 内镜下逆行胰胆管造影术 消炎痛栓 胰腺炎 预防 疗效 Endoscopic retrograde cholangiopancreatography Indomethacin thrombus Pancreatitis Prevention Curative effect
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