摘要
目的:探讨通窍活血汤联合吞咽功能训练对晚期食管癌(EC)伴随吞咽困难病人的疗效。方法:选取98例晚期EC伴随吞咽困难病人,按其意愿分为A组(40例)与B组(58例)。所有病人均采用直线加速器进行放疗,放疗1个疗程后,A组接受吞咽功能训练,B组在A组基础上联合通窍活血汤治疗。依据洼田俊夫饮水实验标准评定2组临床疗效;在治疗前和治疗4周后,比较2组中医症状评分、卡氏功能状态评分(KPS)评分及癌症病人生存质量(QOL-30)评分变化。结果:治疗后,B组的临床总有效率为91.38%,高于A组的72.50%(P<0.05),纳差、吞咽梗阻、疼痛等中医症状评分低于A组(P<0.01),KPS评分和QOL-30评分均高于A组(P<0.01)。结论:通窍活血汤联合吞咽功能训练能够有效提高EC伴随吞咽困难症状病人的临床疗效,促进其吞咽功能恢复,改善各项中医症状,提高生存质量。
Objective:To investigate the effects of Tongqiao Huoxue decoction combined with swallowing function training on the advanced esophageal cancer(EC)complicated with dysphagia.Methods:Ninety-eight patients with advanced EC complicated with dysphagia were divided into group A(40 cases)and group B(58 cases)according to their willingness.All patients were treated with radiotherapy using linear accelerator.After one course of radiotherapy,group A was treated with swallowing function training,and group B was additionally treated with Tongqiao Huoxue decoction on the basis of group A.According to the standard of water drinking test of Watian Junfu,the clinical efficacy in two groups was evaluated.The traditional Chinese medicine symptom score,Karnofsky performance status(KPS)score and quality of life(QOL-30)score were compared between two groups before and after 4 weeks of treatment.Results:After treatment,the total effective rate in group B(91.38%)was higher than that in group A(72.50%)(P<0.05).The scores of anorexia,swallow obstruction and pain of traditional Chinese medicine symptoms in group B were lower than those in group A(P<0.01),and the scores of KPS and QOL-30 in group B were higher than those in group A(P<0.01).Conclusions:Tongqiao Huoxue decoction combined with swallowing function training can effectively improve the clinical efficacy,recovery of swallowing function,various traditional Chinese medicine symptoms and quality of life of patients with EC complicated with dysphagia.
作者
申旭
赵冬梅
赵莉莎
李占林
SHEN Xu;ZHAO Dong-mei;ZHAO Li-sha;LI Zhan-lin(Department of Traditional Chinese Medicine,The First Affiliated Hospital of Northern College,Zhangjiakou Hebei 075000,China)
出处
《蚌埠医学院学报》
CAS
2020年第6期785-787,791,共4页
Journal of Bengbu Medical College
关键词
食管肿瘤
通窍活血汤
吞咽功能训练
吞咽困难
esophageal neoplasms
Tongqiao Huoxue decoction
swallowing function training
dysphagia
