摘要
目的:探讨乳腺癌根治术后皮下积液的相关因素。方法:回顾性分析2018年11月至2019年11月我院进行乳腺癌根治术的350例患者的临床资料,根据术后有无皮下积液分为皮下积液组(n=25)与对照组(n=85)。对两组患者临床资料进行单因素比较,选取存在显著差异的指标行非条件Logistic多元逐步回归分析。结果:肿瘤TNM分期、术后淋巴结清扫数目及范围、术后行放化疗治疗、术中使用生物蛋白胶、体重指数、有无合并症是导致乳腺癌根治术后皮下积液的影响因素(P均<0.05);经非条件Logistic多元逐步回归分析,术后行放化疗治疗、术后淋巴结清扫数目及范围、术中未使用生物蛋白胶、体重指数、有无合并症是导致术后皮下积液的独立危险因素(P<0.05)。结论:术后放化疗、淋巴结清扫数量多及范围广、术中未使用生物蛋白胶、体重指数高及合并有糖尿病是乳腺癌根治术后皮下积液的独立危险因素,临床应采取相应的干预措施,改善患者术后机体恢复。
Objective:To investigate the related factors of subcutaneous hydrops after radical resection of breast cancer.Methods:The clinical data of 350 patients undergoing radical resection of breast cancer in our hospital from November 2018 to November 2019 were retrospectively analyzed,and the patients were divided into subcutaneous hydrops group(n=25)and control group(n=85)according to the postoperative situation.The clinical data of two groups of patients were compared by univariate comparison,and indicators with significant differences were selected for non-conditional Logistic multiple stepwise regression analysis.Results:Tumor TNM staging,quantity and range of postoperative lymph node dissection,intraoperative use of fibrin glue,body mass index and presence or absence of comorbidities were the influencing factors that led to subcutaneous hydrops after radical resection of breast cancer(all P<0.05).Non-conditional Logistic multiple stepwise regression analysis showed that postoperative radiotherapy and chemotherapy,quantity and range of postoperative lymph node dissections,intraoperative non-use of fibrin glue,body mass index and presence of comorbidities were independent risk factors that led to postoperative subcutaneous hydrops(all P<0.05).Conclusion:Postoperative radiotherapy and chemotherapy,high quantity and wide range of lymph node dissection,intraoperative non-use of fibrin glue,high body mass index and diabetes mellitus are independent risk factors for subcutaneous hydrops after radical resection of breast cancer.It is necessary to given interventions to improve postoperative body recovery in clinical application according to the risk sources.
作者
段娟娟
Duan Juanjuan(The 989th Hospital of Joint Logistic Support Force,Luoyang 471000,China)
出处
《甘肃医药》
2020年第1期6-8,13,共4页
Gansu Medical Journal
关键词
乳腺癌根治术
皮下积液
相关因素
radical resection of breast cancer
subcutaneous hydrops
related factors
