摘要
目的探究轻度胃肠炎伴婴幼儿良性惊厥(BICE)与贫血和铁代谢异常之间的关系。方法选取2018年1月至2019年11月佛山市妇幼保健院收治的40例BICE患儿为观察组,同期无惊厥发作的急性胃肠炎患儿为对照组。检测其血红蛋白(Hb)、平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)、平均红细胞血红蛋白浓度(MCHC)、网织红细胞(Ret)、C反应蛋白(CRP)、降钙素原(PCT)、血清铁蛋白(SF)、血清铁(SI)。分析贫血、铁代谢及炎症相关指标与BICE发生的关系。结果观察组炎症相关指标(CRP、PCT)与对照组相比无统计学差异(P>0.05)。观察组的Hb、MCV、Ret、MCH、MCHC与对照组比较,差异均无统计学意义(P>0.05),其中观察提示BICE患儿同时伴有贫血的发生率稍高于对照组,但差异并无统计学意义(P>0.05)。观察组的血清SF和SI显著低于对照组,差异具有统计学意义(P<0.05)。结论机体铁元素的缺乏与BICE的发生密切相关,铁代谢指标或可作为轻度胃肠炎伴婴幼儿良性惊厥患儿的常规检查项目,铁剂补充可能成为BICE防治的新手段。
Objective To study the relationship between iron metabolism and benign infantile convulsions(BICE)with mild gastroenteritis.Methods A total of 40 children with BICE admitted in Foshan maternal and child health care center from Jan 2018 to Nov 2019 and 40 controls with acute gastroenteritis but without convulsions were included in this study.Hemoglobin(Hb),erythrocyte mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH),mean corpuscular hemoglobin concentration(MCHC),reticulocyte(Ret),C-reactive protein(CRP),procalcitonin(PCT),serum ferritin(SF),serum iron(SI)were measured.Analysis of the relationship between anemia,iron metabolism and inflammation-related indicators and BICE was conducted.Results There was no statistical difference in the inflammation-related indicators(CRP,PCT)in the observation group compared with the control group(P>0.05).There was no significant difference in Hb,MCV,Ret,MCH,and MCHC in the observation group compared with the control group(P>0.05).The observations showed that the incidence of anemia with BICE in children was slightly higher than that in the control group,but the difference was not statistically significant(P>0.05).The serum SF and SI of the observation group were significantly lower than those of the control group,the difference was statistically significant(P<0.05).Conclusions The lack of iron in the body is closely related to the occurrence of BICE.The iron metabolism index may be used as a routine inspection item for children with mild gastroenteritis and benign convulsions in infants and young children.Iron supplementation may become a new means of BICE.
作者
戴杰民
刘志刚
李国伟
叶星光
Dai Jiemin;Liu Zhigang;Li Guowei;Ye Xingguang(Southern Medical University Affiliated Foshan Maternal and Child Health Care Hospital,Foshan 528000,China)
出处
《中华肥胖与代谢病电子杂志》
2020年第1期37-40,共4页
Chinese Journal Of Obesity and Metabolic Diseases：Electronic Edition
基金
佛山市卫生健康局医学科研项目(20190120)。
关键词
轻度胃肠炎伴婴幼儿良性惊厥
贫血
铁代谢
Benign infantile convulsion with mild gastroenteritis
Anemia
Iron metabolism
