摘要
目的了解2014-2019年湖南省某三级甲等医院医院感染发生特点和变化趋势,为制定医院感染预防控制和管理措施提供依据。方法采用电子病历调查和床旁调查相结合的方法,对2014-2019年湖南省某三级甲等医院某一时点的医院感染情况进行调查,分析医院感染发生率、感染科室分布、感染部位、病原菌检出和抗菌药物使用及送检情况。结果2014-2019年共调查住院患者5815例,医院感染患者217例(231例次),医院感染现患率为3.23%~4.71%;中心ICU和神经外科医院感染发生率较高;感染部位以下呼吸道感染为主;医院感染病原菌以革兰阴性菌为主,铜绿假单胞菌是检出率最高的多重耐药菌,占36.96%;抗菌药物使用率为29.33%~41.94%,不同年份间使用率比较,差异有统计学意义(χ^2=33.22,P<0.01);治疗性抗菌药物平均使用率为74.74%,药物联用以一联用药为主;治疗药物送检率呈上升趋势,由31.77%上升至61.96%,差异有统计学意义(χ^2=212.69,P<0.01)。结论湖南省某三级甲等医院抗菌药物管理虽有所成效,但仍需进一步加强医院感染防控工作。
Objective To understand the characteristics and trends of hospital infection in a third-level first-class hospital in Hunan Province from 2014-2019,and to provide a basis for the formulation of hospital infection prevention and control measures.Methods A combination of electronic medical record survey and bedside survey was adopted to investigate the hospital infection situation at a certain point in a third-level first-class hospital in Hunan Province from 2014-2019,and the incidence of hospital infection,distribution of infection departments,infection sites,and pathogen detection and using of antibacterial drugs and inspection situation were analyzed.Results From 2014-2019,a total of 5815 inpatients were investigated,and 217 patients with hospital infections(231 case-times),and the prevalence of hospital infections was 3.23%-4.71%.The incidence o f hospital infection in ICU and neurosurgery was higher,lower respiratory tract infections were the main infection sites.Gram-negative bacteria were the main pathogens of hospital infections,and Pseudomonas aeruginosa was the multi-drug resistant bacteria with the highest detection rate,accounting for 36.96%.The usage rate of antibacterial drugs was 29.33%-41.94%,and the difference between different years was statistically significant(χ^2=33.22,P<0.01).The average usage rate of therapeutic antibacterial drugs was 74.74%,and the drug combination was mainly one medicine.The inspection rate of therapeutic drugs was on the rise,from31.77%to 61.96%,and the difference was statistically significant(χ^2=212.69,P<0.01).Conclusion Although the management of antibacterial drugs in a third-level first-class hospital of Hunan Province has been effective,it is necessary to further strengthen the work of prevention and control of hospital infection.
作者
符昌艳
李贤
龙鸣燕
谭利明
陈露
周璐璐
张天成
FU Chang-yan;LI Xian;LONG Ming-yan;TAN Li-ming;CHEN Lu;ZHOU Lu-lu;ZHANG Tian-cheng(School of Public Health,University of South China,Hengyang Hunan,421001,China;Department of Hospital Infection Management,Affiliated Nanhua Hospital,University of South China,Hengyang Hunan,421001,China)
出处
《职业与健康》
CAS
2020年第7期905-909,共5页
Occupation and Health
基金
湖南省科技发展计划专项资金项目(2018ZK4048)。
关键词
医院感染
现患率
感染部位
抗菌药物
Hospital infection
Prevalence rate
Infected site
Antibiotics
