摘要
病理性瘢痕是创伤后皮肤组织过度增生的结果,常见的致病因素包括外伤、烧伤、手术、疫苗接种、皮肤穿刺、痤疮和带状疱疹等,但具体发病机制仍未完全阐明。病理性瘢痕可对患者的生理功能和心理健康造成不良影响。传统的治疗手段包括压迫治疗、硅胶制剂、药物治疗、手术、放射治疗等,新的治疗方法包括激光、自体脂肪移植、免疫疗法、基因疗法等,但尚未有令人满意的单一疗法,因此综合治疗仍是目前临床的首选。
Pathological scars are the result of abnormal hypertrophy of scar tissue,whose common causes include trauma,burns,surgery,vaccination,skin puncture,acne,herpes zoster,etc.The pathogenesis is not yet fully elucidated.Pathological scars can affect the physiological function and mental health of patients,so the treatment is particularly important.Traditional therapeutic strategies include compression therapy,silicon gel,drug therapy,surgery,radiotherapy,etc.In recent years,there are some emerging therapies,such as laser,autologous fat transplantation,immunotherapy,gene therapy,etc.However,there is no monotherapy that can achieve satisfactory result so that comprehensive treatment is still the first choice in clinical practice.
作者
马倩玉
武晓莉
MA Qianyu;WU Xiaoli(Department of Plastic and Reconstructive Surgery,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China)
出处
《组织工程与重建外科杂志》
2020年第1期1-5,26,共6页
Journal of Tissue Engineering and Reconstructive Surgery
