摘要
目的:探讨经皮肾镜取石术(PCNL)与经输尿管软镜取石术(FURL)治疗肾结石的临床效果.方法:选取2015年7月-2019年6月于本院治疗的肾结石患者80例,按随机数字表法分为对照组与观察组,每组40例.对照组进行PCNL治疗,观察组进行FURL治疗.比较两组围术期指标、中性粒细胞明胶酶相关载脂蛋白(NGAL)、丙二醛(MDA)及超氧化物歧化酶(SOD)水平、结石清除率及并发症发生情况.结果:观察组术中出血量少于对照组,且住院时间短于对照组(P<0.05).术后,两组NGAL与MDA均高于术前,而SOD均低于术前(P<0.05).术后,观察组NGAL与MDA均低于对照组,而SOD高于对照组(P<0.05).观察组并发症发生率低于对照组(P<0.05).两组结石清除率比较,差异无统计学意义(P>0.05).结论:FURL治疗肾结石可减少术中出血量与并发症,创伤应激轻微,有利于缩短住院时间.
Objective:To explore the clinical effect of percutaneous nephrolithotomy(PCNL)and flexible ureteroscope lithotripsy(FURL)for the treatment of renal calculi.Method:A total of 80 patients with renal calculi treated in our hospital from July 2015 to June 2019 were selected.They were divided into control group and observation group according to the random number table method,40 cases in each group.The control group treated with PCNL,and the observation group treated with FURL.Perioperative index,the levels of neutrophil gelatinase-associated lipocalin(NGAL),malondialdehyde(MDA),superoxide dismutase(SOD),stone clearance rate and complications were compared between the two groups.Result:The amount of intraoperative blood loss in the observation group was lower than that in the control group,and the hospital stays was lower than that in the control group(P<0.05).After surgery,NGAL and MDA in both groups were higher than those before surgery,while SOD in both groups were lower than those before surgery(P<0.05).After surgery,NGAL and MDA in the observation group were lower than those in the control group,while SOD was higher than that in the control group(P<0.05).The incidence of complications in the observation group was lower than that in the control group(P<0.05).There was no significant difference in stone clearance rate between the two groups(P>0.05).Conclusion:FURL treatment of renal calculi can reduce intraoperative blood loss and complications,mild traumatic stress,which is beneficial to shorten the hospitalization time.
作者
叶韬
李成文
高加胜
张海峰
李志坚
YE Tao;LI Chengwen;GAO Jiasheng;ZHANG Haifeng;LI Zhijian(Jiujiang First People’s Hospital of Jiangxi Province,Jiujiang 332000,China)
出处
《中国医学创新》
CAS
2020年第16期127-130,共4页
Medical Innovation of China
基金
九江市科技计划项目(2017101)。
