摘要
随着外科学的发展和进步,越来越多的患者接受手术,术后谵妄(postoperative delirium,POD)是常见的并发症之一,越来越受到临床医师的重视,但POD发病机制尚不完全清楚,诊断上仍存在一定困难,POD的表现多样,易于漏诊,缺乏特异性生化标志物的辅助。目前POD的治疗仍存在许多困难,尤其是缺乏有效的药物。文章从POD的诊断、发病机制、预防和治疗等方面进行综述,为下一步研究探索方向。
With the rapid development and huge progress of surgery,more and more patients choose to undergo surgery.Postoperative delirium is a common complication which has attracted increasing attention.However,the pathogenesis of postoperative delirium remains unclear,and it is still not easy to diagnose the disease.Postoperative delirium has diverse manifestations and is easy to be misdiagnosed,without specific biochemical markers.The treatment of postoperative delirium is still difficult,especially the lack of effective drugs.This paper summarized the diagnosis,pathogenesis,prevention and treatment of postoperative delirium,so as to facilitate future research.
作者
蔡玲
朱凯敏
沈美华
何虹
Cai Ling;Zhu Kaimin;Shen Meihua;He Hong(Department of Anesthesiology,Women and Children's Healthcare of Changning Distric,Shanghai 200051,China;Departmenl of Inten-sive Care Medicine,Shanghai Prorincial Corp Hospial of Chinese people's Armed Police Forces,Shanghai 201103,China)
出处
《国际麻醉学与复苏杂志》
CAS
2020年第4期411-416,共6页
International Journal of Anesthesiology and Resuscitation
关键词
术后谵妄
认知障碍
Postoperative delirium
Cognitive disorder
