摘要
目的了解兰州地区儿童急性中耳炎(acute otitis media,AOM)的发病特点,并进一步探讨儿童AOM与环境气象因素的相关性。方法收集2015-2017年兰州两所三甲医院门诊及急诊就诊的AOM患者的ID号、年龄、性别、就诊日期、诊断等相关信息,及同期兰州市空气质量指数(air quality index,AQI)、环境气象数据(PM2.5、PM10、CO、NO2、SO2、O3、平均气温、平均气压、平均风速、平均湿度),并分析环境气象因素与儿童AOM发病之间的相关性。结果2015、2016及2017年儿童AOM患儿就诊数量分别为2576、2934和2871例,3年总体差异无统计学意义(P=0.818);每年就诊情况均在12月份达到高峰,8月份最少,2月份次之,夏季明显少于其他季节(P<0.05),其他三季无明显差异(P>0.05)。1岁以内婴幼儿AOM发病占一定比例,在4岁左右出现一个峰值,6-7岁左右出现第二个发病峰值,之后随着年龄增大就诊数量逐渐减少。在不同年龄段,男性患儿就诊量均高于女性(P=0.000);儿童AOM日就诊人数与AQI、PM2.5、PM10、CO、NO2、SO2呈正相关,与O3呈负相关,与平均气温呈负相关(r=-0.284,P=0.000),与平均气压呈正相关(r=0.129,P=0.000),而与相对湿度、平均风速无相关性(r=-0.011 P=0.716,r=-0.057 P=0.061)。环境气象因素对儿童AOM的发病存在滞后效应。结论兰州地区儿童AOM与环境气象因素之间存在相关性。
Objective To study characteristics of acute otitis media(AOM)in children and their correlation with environmental-meteorological factors in Lanzhou.Methods Clinical data on children with AOM seen in Otolaryngology outpatient clinics and emergency departments were collected from 2015 to 2017 at two top-tier hospitals in Lanzhou,including age,sex,date of visit and diagnosis.The air quality index(AQI)and environmental-meteorological data(PM2.5,PM10,CO,NO2,SO2,O3,average temperature,average air Pressure,average wind speed,average humidity)of the same period were also collected and analyzed for potential correlation with AOM in children.Results Annual number of children seen for AOM was 2576 in 2015,2934 in 2016 and 2871 in 2017,respectively(P=0.818),with visits peaking in December,reaching a minimum in August(followed by February)(P<0.05)and showing no statistical differences in other seasons(P>0.05).While AOM was seen in a certain number of children younger than one year,its incidence showed a peak in those of about 4 years of age and a second peak in those of 6-7 years,followed by a gradual decline in older children.Incidence of AOM was higher in boys than in girls(P=0.000).It was found to show a positive correlation tendency with AQI,PM2.5,PM10,CO,NO2 and SO2,and a negative correlation tendency with O3.It also demonstrated a negative correlation with average temperature(r=-0.284,P=0.000)and a positive correlation with average air pressure(r=0.129,P=0.000),but no correlation with relative humidity or average wind speed(r=-0.011,P=0.716 and r=-0.057,P=0.061,respectively).Variation in incidence of AOM in children seemed to lag behind those in environmental meteorological factors.Conclusion Our data show some correlation between environmental meteorological factors and incidence of AOM in children.
作者
王新兰
王梅
徐百成
王金艳
钟翠萍
WANG Xinlan;WANG Mei;XU Baicheng;Wang Jinyan;ZHONG Cuiping(Department of Otolaryngology-Head and Neck Surgery,940th Hospital,Chinese PLA Joint Logistics Support Unit,Lanzhou 730050;Graduate School of Clinical Medicine,Ningxia Medical University,Yinchuan,750004;Department of Otolaryngology Head and Neck Surgery,Lanzhou University Second Affiliated Hospital,Lanzhou 730030;School of Atmospheric Sciences,Lanzhou University,Lanzhou 730000)
出处
《中华耳科学杂志》
CSCD
北大核心
2020年第3期527-533,共7页
Chinese Journal of Otology
基金
甘肃省重点研发计划项目(18YF1FA132)
甘肃省卫生行业科研计划项目(GSWGKY8-25)
2018年度军队医学科技青年培育计划项目(18QNP047)。
关键词
急性中耳炎
大气污染物
气象因素
儿童
Acute otitis media
Air pollutions
Meteorological factors
Children
