摘要
目的:总结导致多重耐药菌感染的主要危险因素并提出相应的防控措施。方法:抽选2017年1月至2019年12月期间于本院接受治疗且发生多重耐药菌感染的429例患者,回顾分析患者的临床资料,观察多耐药菌株的分布情况,分析导致多重耐药菌感染的主要危险因素,并制定防控多重耐药菌感染的措施。结果:429例患者共检出429株多耐药菌株,其中铜绿假单胞菌101株(23.54%),肺炎克雷伯菌84株(19.58%),金黄色葡萄球菌67株(15.62%),大肠埃希菌63株(14.69%),鲍曼不动杆菌44株(10.26%),其他77株(17.95%)。多耐药菌株的分布部位主要为:下呼吸道235例(54.78%)、泌尿系统119例(27.74%)、上呼吸道46例(10.72%)、切口25例(5.83%)以及其他部位4例(0.93%)。碳青霉烯类药物、导管留置时间、机械通气时间、抗生素使用种类是导致多重耐药菌感染的主要危险因素。结论:铜绿假单胞菌、肺炎克雷伯菌、金黄色葡萄球菌、大肠埃希菌、鲍曼不动杆菌是多重耐药菌最常见的菌株,多重耐药菌主要分布在上呼吸道、下呼吸道、泌尿系统、切口,使用碳青霉烯类药物、抗生素使用种类过多、导管留置时间过长、机械通气时间过长是导致多重耐药菌感染的主要危险因素,给予针对性干预可减少多重耐药菌感染的发生。
Objective:To summarize the main risk factors leading to the infection of multi-drug resistant bacteria and put forward corresponding prevention and control measures.Methods:A total of 429 patients who were treated in our hospital from January 2017 to December 2019 and had multi-drug resistant infections were selected.The clinical data of the patients were retrospectively analyzed to observe the distribution of multi-drug resistant strains and analyze the results of multi-drug resistance.The main risk factors for bacterial infections,and formulate measures to prevent and control infections with multi-drug resistant bacteria.Results:A total of 429 multi-drug resistant strains were detected in 429 patients,including 101 strains of Pseudomonas aeruginosa,84 strains of Klebsiella pneumoniae,67 strains of Staphylococcus aureus,63 strains of Escherichia coli,and Bowman immobility 44 strains of Bacillus and 77 others.The distribution sites are:235 cases of lower respiratory tract,119 cases of urinary system,46 cases of upper respiratory tract,25 cases of incision and 4 cases of other parts.Carbapenem drugs,catheter indwelling time,mechanical ventilation time,and antibiotic use types are the main risk factors for multi-drug resistant infections.Conclusion:Pseudomonas aeruginosa,Klebsiella pneumoniae,Staphylococcus aureus,Escherichia coli,Acinetobacter baumannii are the most common strains of multi-drug resistant bacteria,multi-drug resistant bacteria are mainly distributed in the upper respiratory tract,lower Respiratory tract,urinary system,incision,use of carbapenems,excessive use of antibiotics,excessive catheter indwelling time,and long mechanical ventilation time are the main risk factors for multi-drug resistant infections,and targeted intervention can reduce Occurrence of multi-drug resistant bacteria infection.
作者
毛艳芳
赵连英
朱正娟
MAO Yan-fang;ZHAO Lian-ying;ZHU Zheng-juan(Funing County People’s Hospital of Jiangsu Province,Yancheng Jiangsu 224400,China)
出处
《医学食疗与健康》
2020年第12期217-218,共2页
Medical Diet and Health
关键词
多重耐药菌
医院感染
危险因素
防控措施
Multi-drug Resistant Bacteria
Nosocomial Infection
Risk Factors
Prevention and Control Measures
