摘要
目的 以可视化形式了解我国革兰阳性菌(G+菌)所致脓毒症相关领域的研究现状,明确研究内容,分析其大致研究方向,从而掌握近年研究热点话题。方法 应用计算机检索中国生物医学文献服务系统(SinoMed)从建库至2019年10月以中文形式全文发表的G+菌所致脓毒症相关文献。对相关文献发表年份、发表期刊、研究机构和作者的分布及趋势进行统计,并采用Ucinet 6.0软件绘制作者的社会网络关系图,分析其内在联系。提取相关文献的主题词,采用Ucinet 6.0软件中的NetDraw按照中心度排列各主题词之间的关系,采用书目信息共现分析系统软件(BICOMS2软件)对高频主题词进行归类并生成可视化矩阵,采用图形聚类工具软件(gCLUTO软件)对高频主题词进行聚类分析并生成可视化曲面图,分析当前G+菌所致脓毒症的研究热点、研究趋势及研究方向。结果 共检索G+菌所致脓毒症相关文献1 976篇,排除会议摘要、新闻报道、研究资讯、内容缺失或与主题不符的文献26篇,最终共1 950篇纳入可视化分析。发文量分析显示,1979至1992年G+菌所致脓毒症相关研究较少,从2008年开始呈几何倍数增长,2008至2018年累计发文量达1 144篇,约占总发文量的58.67%(1 144/1 950)。1979至2019年累计发文量超过5篇的院所共23家,其中达到或超过10篇的院所有6家,超过20篇的院所有1家;载文量超过100篇的期刊仅5本;参与相关文章撰写的作者5 381人,但累计发文量超过10篇的高产作者不多,且未见跨省市院所之间的合作关系。对出现频次超过5次的103个高频主题词进行社会网络分析显示,G+菌所致脓毒症研究主要围绕"脓毒症"展开,包括耐药性强的金黄色葡萄球菌所致脓毒症的发病率呈上升趋势,特别是免疫力较为低下的新生儿和儿童;治疗药物的选择逐渐向抗耐药性较强的糖肽类、人工合成的唑烷酮类抗菌药物发展。针对G+菌所致�
Objective To understand the current situation of research in the field of sepsis caused by Gram positive bacteria(G+bacteria)in China,to clarify the research content and analyze its general research direction,so as to find the hot topics of research in recent years.Methods The literatures in SinoMed related to sepsis caused by G+bacteria and published in Chinese from building database to October 2019 were screened.The distribution and trend of the published year,journals,research institutions and researchers of relevant literature were analyzed,and Ucinet 6.0 software was used to draw the social network graph of the researchers and to analyze their internal relations.The subject words of related literatures were extracted.The relationship among the subject words in related literatures was arranged according to the centrality by NetDraw in Ucinet 6.0 software,the bibliographic information co-occurrence analysis system software(BICOMS2 software)was used to classify the subject words and the visualization matrix was generated.The graph clustering tool software(gCLUTO software)was used to cluster the subject words,and the visualization surface graph was generated to analyze the current research hot spot,research trend and research direction of G+bacteria-induced sepsis.Results A total of 1976 literatures about sepsis caused by G+bacteria were retrieved,and 26 literatures in conference summaries,news reports,research information,missing content,or inconsistent with the theme were excluded.Finally,a total of 1950 literatures were enrolled in final analysis.The number of published literatures analysis showed that from 1979 to 1992,there were few studies about sepsis caused by G+bacteria,which increased geometrically from 2008,and the number of literatures published from 2008 to 2018 was 1144,accounting for 58.67%(1144/1950).From 1979 to 2019,23 high-yield institutions published more than 5 literatures,of which 6 were institutions with 10 or more literatures,and only one institution with more than 20 literatures.There we
作者
王东亮
赵婧
何天鹏
王泉超
蒋晓颖
袁媛
Wang Dongliang;Zhao Jing;He Tianpeng;Wang Quanchao;Jiang Xiaoying;Yuan Yuan(Department of Critical Care Medicine,Gansu Provincial Hospital,Lanzhou 730000,Gansu,China;Gansu University of Traditional Chinese Medicine,Lanzhou 730000,Gansu,China)
出处
《中华危重病急救医学》
CAS
CSCD
北大核心
2020年第3期294-300,共7页
Chinese Critical Care Medicine
基金
甘肃省自然科学研究基金计划项目(1010RJZA172)
甘肃中医药管理局科研项目(GZK-2019-42)。
关键词
革兰阳性菌
脓毒症
聚类分析
信息可视化
Gram positive bacteria
Sepsis
Cluster analysis
Information visualization
