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电视胸腔镜手术对胸腺瘤合并肌无力患者的短期疗效及预后观察 被引量:6

Short-term Efficacy and Prognosis of Video-assisted Thoracoscopy in Patients with Thymoma and Muscle Weakness
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摘要 目的探讨电视胸腔镜手术(Video assisted thoracoscopic surgery,VATS)对胸腺瘤合并肌无力患者的疗效。方法回顾性分析40例胸腺瘤合并肌无力患者的临床资料,依据所选术式的不同分为观察组(实施VATS治疗,20例)与对照组(实施开胸手术治疗,20例)。术后随访1年,评价2组患者临床疗效,同时比较2组患者手术相关指标、并发症及生活质量。结果与对照组患者相比,观察组患者临床治疗总有效率较高,差异有统计学意义(χ^2=3.906,P=0.018)。与对照组相比,观察组患者手术与住院时间均较短,术中出血量、胸腔引流量均较少,差异有统计学意义(t=4.894、5.292、5.628、10.277,P均=0.000)。与对照组患者相比,观察组患者并发症总发生率较低,差异有统计学意义(χ^2=4.329,P=0.037)。与对照组患者相比,观察组患者角色功能、情绪功能、躯体功能、认知功能、社会功能、总生活质量评分均较高,差异有统计学意义(t=2.201、2.127、2.116、3.967、2.537、3.185,P=0.034、0.040、0.041、0.000、0.015、0.003)。结论VATS治疗胸腺瘤合并肌无力可有效提高治疗有效率,减少术后并发症发生,且具有创伤小、术后恢复速度快等特点,有助于改善患者生活质量。 Objective To investigate the effect of video assisted thoracoscopic surgery(VATS)on patients with thymoma and muscle weakness.Methods The clinical data of 40 patients with thymoma and myasthenia gravis were retrospectively analyzed.They were divided into the observation group(implemented VATS treatment,20 cases)and the control group(20 patients underwent thoracotomy),according to the selected surgery.Followed up for 1 year after operation,and evaluated the clinical efficacy of the 2 groups.At the same time,the surgical indicators,complications and quality of life were compared between the 2 groups.Results Compared with the patients in the control group,the total effective rate of clinical treatment in the observation group was higher,and the difference was statistically significant(χ^2=3.906,P=0.018).Compared with the control group,the patients in the observation group had both surgery and hospitalization.Shorter,less intraoperative blood loss and thoracic drainage,the differences were statistically significant(t=4.894、5.292、5.628、10.277,P=0.000);Compared with patients in the control group,the total complications of the observation group were The incidence rate was relatively significant,and the difference was statistically significant(χ^2=4.329,P=0.037).Compared with the control group,the observation group had role function,emotional function,physical function,cognitive function,social function,and total quality of life scores.The difference was statistically significant(t=2.201、2.127、2.116、3.967、2.537、3.185,P=0.034、0.040、0.041、0.000、0.015、0.003).Conclusion VATS can effectively improve the treatment efficiency and reduce the incidence of postoperative complications in patients with thymoma and myasthenia,and it has the characteristics of less trauma and fast postoperative recovery,which can help improve the quality of life of patients.
作者 李奇 LI Qi(Kaifeng People's Hospital,Kaifeng,475002)
出处 《实用癌症杂志》 2020年第6期955-958,共4页 The Practical Journal of Cancer
关键词 胸腺瘤合并肌无力 电视胸腔镜手术 开胸手术 生活质量 Thymoma with muscle weakness Video-assisted thoracoscopy Thoracotomy Quality of life
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