摘要
胸主动脉夹层是一种严重危及人类健康的心血管疾病,临床上的主要治疗方式为胸腔内修复术(TEVAR)。结合开窗技术的TEVAR(ISF-TEVAR)可用于治疗累及主动脉弓及其弓上分支血管的复杂病例。对一例主动脉夹层建立ISF-TEVAR术后的主动脉模型,开展血液两相流动数值模拟。通过考察血流动力学参数,定量探究ISF-TEVAR手术疗效;同时通过虚拟手术,缩短开窗支架在主动脉弓部的伸出长度,分别构建"半伸出"和"无伸出"两例术后模型,对比探究开窗支架的伸出长度对术后血液流动的影响。结果表明,开窗支架伸出段对血液动力学参数有显著影响,适当缩短伸出段长度有助于提升手术疗效。
Thoracic aortic dissection is a cardiovascular disease which seriously endangers human health. The main clinical treatment is thoracic endovascular aortic repair( TEAVR). TEVAR with in situ fenestration technique( ISF-TEVAR) can be used to treat complex cases involving the aortic arch and its branches. In this study,aortic geometry model of a patient suffering from aortic dissection treated by ISF-TEVAR was reconstructed,and two-phase blood flow simulation was carried out. The efficacy of ISF-TEVAR was quantitatively explored by assessing the hemodynamics.Meanwhile,the protruding length of the fenestration stent in the aortic arch was shortened by virtual surgery,and the"half protrusion"and"no protrusion"postoperative models were compared to reveal the effect of the protruding length on postoperative blood flow. Results show that appropriately shortening the protrusion length of the stent-graft improves the efficacy of ISF-TEVAR.
作者
乔永辉
罗坤
樊建人
毛乐
竺挺
QIAO Yonghui;LUO Kun;FAN Jianren;MAO Le;ZHU Ting(State Key Laboratory of Clean Energy Utilization,Zhejiang University,Hangzhou 310027,China;Department of Vascular Surgery,Zhongshan Hospital,Fudan University,Shanghai 200032,China)
出处
《中国科学院大学学报（中英文）》
CSCD
北大核心
2020年第2期192-197,共6页
Journal of University of Chinese Academy of Sciences
基金
国家自然科学基金(51576049)资助。
关键词
主动脉夹层
胸主动脉腔内修复术
原位开窗
左锁骨下动脉
两相流
aortic dissection
thoracic endovascular aortic repair
in situ fenestration
left subclavian artery
two-phase flow
