摘要
目的:考察冠心宁注射液的配伍稳定性。方法:根据用法用量,分别将冠心宁与5%葡萄糖注射液、0.9%氯化钠注射液配伍后,考察室温放置不同时间后,其性状、pH值、渗透压摩尔浓度、吸光度、不溶性微粒及含量的变化。结果:冠心宁注射液与5%葡萄糖注射液、0.9%氯化钠注射液配伍后12h内质量稳定。结论:冠心宁注射液可与5%葡萄糖注射液、0.9%氯化钠注射液配伍。
Objective:To investigate on the compatibility stability of Guanxinning Injection.Methods:According to the usage and dosage,the changes of characters,pH value,osmotic molar concentration,absorbance,insoluble particles and content after being placed at room temperature for different times were investigated.Results:The quality of Guanxinning injection was stable within 12 hours after compatibility with 5%glucose injection and 0.9%sodiμm chloride injection.Conclusion:Guanxinning injection can be compatible with 5%glucose injection and 0.9%sodiμm chloride injection.
作者
张睿智
丁艳谱
李响明
宋娜娜
张旭
郝欣岭
孙胜斌
Zhang Ruizhi;Ding Yanpu;Li Xiangming;Song Nana;Zhang Xu;Hao Xinling;Sun Shengbin(Shineway Pharmaceutical Group Co.,Ltd,Shijiazhuang 051430,China;State-Local Joint Engineering Laboratory of New Drugs Development Technology for TCM Injection,Shijiazhuang 051430,China)
出处
《亚太传统医药》
2020年第4期63-66,共4页
Asia-Pacific Traditional Medicine
关键词
冠心宁注射液
葡萄糖注射液
氯化钠注射液
配伍
稳定性
Guanxinning Injection
Glucose Injection
Sodiμm Chloride Injection
Compatibility
Stability
