摘要
目的:通过分析晚期非小细胞肺癌证候分布规律以归纳晚期肺癌的常见临床证型。方法:采集晚期肺癌证候学的调查问卷资料,对调查表中的20余个中医症状、舌象和脉象建立数据库,统计各个症状的频数,排除低概率症状,运用因子分析法进行归类,结合专家辨证,进行晚期肺癌的证候分布分析。结果:最终纳入统计病例224例,对17个变量进行因子分析,统计出5组症状,结合专家辨证,得出最常见的证型为气虚痰毒证97例(43.30%)与阴虚痰毒证85例(37.95%)。结论:晚期肺癌最常见的证型为气虚痰毒证与阴虚痰毒证。
Objective:By analyzing the distribution of syndromes in advanced non-small cell lung cancer,it can summarize the common clinical syndromes of advanced lung cancer.Methods:Collect questionnaire data on syndromes of advanced lung cancer,establish a database of more than 20 TCM symptoms,tongue manifestation and pulse manifestation in the questionnaire,count the frequency of each symptom,eliminate low-probability symptoms,classify by factor analysis,and combine experts syndrome differentiation to analysis the distribution of syndromes in advanced lung cancer.Results:224 cases were eventually included in the statistical case.Factor analysis of 17 variables,statistics of 5 groups of symptoms,combined with expert syndrome differentiation,the most common syndromes were syndrome of qi deficiency phlegmatic toxin of 97 cases(43.30%)and yin deficiency phlegmatic toxin of 85 cases(37.95%).Conclusion:The most common syndromes of advanced lung cancer are syndrome of qi deficiency phlegmatic toxin and yin deficiency phlegmatic toxin.
作者
陈滨海
张雅丽
李晓娟
楼招欢
高文仓
张光霁
CHEN Bin-hai;ZHANG Ya-li;LI Xiao-juan;LOU Zhao-huan;GAO Wen-cang;ZHANG Guang-ji(The Second Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310005,China;The First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310006,China;Zhejiang Chinese Medical University,Hangzhou 310053,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2020年第4期1976-1979,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(No.81573962)
浙江省中医药科学研究基金计划项目(No.2016ZA098,No.2019ZA062)。
关键词
肺癌
转移
痰毒
中医证候
临床研究
Lung cancer
Metastasis
Phlegmatic toxin
TCM syndrome
Clinical studies
