摘要
目的探讨稳心颗粒联合胺碘酮治疗房颤并频发室性心律失常的临床疗效。方法选取医院2018年1月至2018年12月收治的房颤并频发室性心律失常患者72例,分为观察组和对照组,各36例。观察组患者以稳心颗粒联合胺碘酮治疗,对照组患者以胺碘酮治疗。结果两组总有效率无显著性差异(P>0.05)。治疗后,两组患者的室性心律失常均显著减少(P<0.05),胸闷、心悸等症状均显著减轻;治疗后两组均无明显黑朦、头晕等不良反应发生,治疗后RR长间期观察组为3例,显著少于对照组的9例(P<0.05),但两组均未出现>2.5 s RR长间期发生。治疗前后两组患者的血糖、血脂、凝血机制、尿常规、肝功能、肾功能、电解质、甲状腺功能等实验室检查指标无显著改变。结论采用稳心颗粒联合胺碘酮治疗房颤并频发室性心律失常,可显著改善病情,避免长RR间期的发生。
Objective To investigate the clinical effect of Wenxin Granules combined with amiodarone in the treatment of atrial fibrillation and frequent ventricular arrhythmia.Methods From January 2018 to December 2018,72 patients with atrial fibrillation and frequent ventricular arrhythmia were divided into observation group and control group,36 cases in each group.The observation group was treated with Wenxin Granules and amiodarone,while the control group was treated with amiodarone.Results There was no significant difference in the total effective rate between the two groups(P>0.05).After treatment,the ventricular arrhythmia and chest distress,palpitation and other symptoms were significantly reduced in both groups(P<0.05).After treatment,there were no adverse reactions such as blackness and dizziness in both groups.After treatment,the patients with long RR interval in the observation group was 3 cases,which were significantly lower than 9 cases in the control group(P<0.05),but there was no long RR interval with more than 2.5 s in both groups.Before and after treatment,there were no significant changes in blood glucose,blood lipid,coagulation mechanism,urine routine,liver function,renal function,electrolyte,thyroid function and other laboratory indexes.Conclusion Wenxin Granules combined with amiodarone in the treatment of atrial fibrillation and frequent ventricular arrhythmia can significantly improve the condition and avoid long RR interval.
出处
《中国药业》
CAS
2019年第S01期40-41,共2页
China Pharmaceuticals
关键词
房颤
频发室性心律失常
稳心颗粒
胺碘酮
临床疗效
atrial fibrillation
frequent ventricular arrhythmia
Wenxin Granules
amiodarone
clinical efficacy
