摘要
心血管疾病是危害人类健康的首要原因,而动脉粥样硬化是多种心脑血管疾病的病理基础,近年来针对动脉粥样硬化斑块稳定性诊断和治疗的研究层出不穷。斑块内细胞焦亡的发生直接关系着斑块的稳定性,因此对细胞焦亡的调控对稳定斑块尤为重要。现总结在动脉粥样硬化中新发现的发挥调节作用的microRNAs和一些microRNAs通过调节细胞焦亡在动脉粥样硬化中的作用。
Cardiovascular diseases are the primary cause of harm to human health,and atherosclerosis is the pathological basis of a variety of cardiovascular diseases.The occurrence of pyroptosis in plaques is directly related to the stability of plaques,so the regulation of pyroptosis is particularly important to stabilize plaques.This paper aims to summary newly discovered microRNAs that play a regulatory role in atherosclerosis and some microRNAs that regulate the role of pyroptosis in atherosclerosis.
作者
王盛姣
关秀茹
WANG Shengjiao;GUAN Xiuru(Harbin Medical University Graduate School,Harbin 150081,Heilongjiang,China;Clinical Laboratory of The First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang,China)
出处
《心血管病学进展》
CAS
2020年第5期521-523,共3页
Advances in Cardiovascular Diseases
基金
国家自然科学基金(81672084)。
