摘要
目的探讨儿童视网膜母细胞瘤的临床病理特点和治疗方法。方法选取2017年6月至2019年10月间山东省立第三医院收治的62例儿童视网膜母细胞瘤,分析患儿的年龄分布、病理特点和治疗方法。结果0~3岁者50例(80.7%),3~5岁者7例(11.3%),5岁以上者5例(8.1%),年龄(1.82±1.12)岁。除5眼于入院时眼球已被摘除外,余76眼临床分期:A^C期15.8%(12/76),D期40.8%(31/76),E期43.4%(33/76);未分化型55眼(72.4%),分化型26眼(27.6%)。未分化型中,视神经断端未受侵犯有51眼(92.7%),视神经断端受侵犯有4眼(7.3%);分化型中,视神经断端未受侵犯有24眼(92.3%),视神经断端受侵犯有2眼(7.7%)。结论视网膜母细胞瘤危害大,且早期宣传、早筛查、早诊断和早治疗,能够更好地挽救患儿的视力和生命。
Objective To investigate the clinicopathological features and treatment of retinoblastoma in children.Methods A retrospective analysis was performed on 62 children with retinoblastoma treated at Shandong Provincial Third Hospital from June 2017 to October 2019.Age distribution,pathological features and treatment methods were analyzed.Results There were 50 children(80.7%)between 0 and 3 years old,7 children(11.3%)between 3 and 5 years old,and 5 children(8.1%)above 5 years old.The mean age was 1.82±1.12 years old.Except for 5 eyes that had been removed on admission,the remaining76 eyes were clinically divided according to International Intraocular Retinoblastoma Classification(IRC)criteria:stage A to C accounted for 15.8%(12/76),stage D 40.8%(31/76),and stage E 43.4%(33/76)with 55 eyes(72.4%)undifferentiated and 26 eyes differentiated(27.6%).For the undifferentiated,51 eyes(92.7%)were free from optic nerve invasion,and invasion of the cut end section of the optic nerve occurred in 4 eyes(7.3%).For the differentiated,24 eyes(92.3%)were free from optic nerve invasion,and invasion of the cut end section of the optic nerve occurred in 2 eyes(7.7%).Conclusion Retinoblastoma is very dangerous and causes great harm to children.Early publicity,screening,diagnosis and treatment can protect children’s vision and life from the harm.
作者
闫丽
于晓明
张秀萍
YAN Li;YU Xiao-ming;ZHANG Xiu-ping(Department of Ophthalmology,Shandong Provincial Third Hospital,Jinan 250031,China)
出处
《中国肿瘤临床与康复》
2020年第4期397-399,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
