摘要
目的:探究氨溴索联合多巴胺治疗方案对小儿上呼吸道感染炎性因子的影响。方法:将我院收治的81例上呼吸道感染患儿,随机分为两组,对照组40例给予常规治疗,观察组41例给予氨溴索联合多巴胺治疗方案,将两组患儿临床疗效、炎性因子及体温恢复、咳嗽消除与咽部充血消除时间进行记录和比较。结果:观察组临床总疗效97.56%,比对照组77.50%高(P<0.05);观察组患儿CRP水平(10.15±6.48)mg/L、TNF-α水平为(14.29±5.40)pg/ml、PCT水平为(0.23±0.05)ng/ml、IL-6水平为(30.51±6.80)pg/ml、IL-8水平为(9.28±2.66)pg/ml均低于对照组(P<0.05);观察组患儿体温恢复时间(2.74±0.90)d、咳嗽消除时间(3.62±0.83)d及咽部充血消除时间(3.83±1.21)d均低于对照组,差异具有统计学意义(P<0.05)。结论:上呼吸道感染患儿给予氨溴索联合多巴胺治疗方案,能够显著提升患儿的临床治疗效果,有效减少炎性因子,缩短治疗时间。
Objective:To investigate the effect of ambroxol combined with dopamine on inflammatory factors in children with upper respiratory tract infection.Methods:81 children with upper respiratory tract infection admitted to our hospital were randomized into two groups:41 patients in the observation group and 40 patients in the control group.Patients in the control group received routine treatment,while patients in the observation group were given the treatment of the combination of ammonia bromide and dopamine,then the clinical efficacy,inflammatory factors and body temperature recovery,cough elimination and pharyngeal congestion elimination time of both groups were recorded and compared.Results:The total clinical efficacy of the observation group was 97.56%,higher than 77.50%of the control group(P<0.05);CRP level(10.15±6.48)mg/L,TNF-αlevel(14.29±5.40)pg/ml,PCT level(0.23±0.05)ng/ml,IL-6 level(30.51±6.80)pg/ml and IL-8(9.28±2.66)pg/ml were observed in the observation group,which were lower than those in the control group(P<0.05);and the recovery time of body temperature(2.74±0.90)d,cough elimination time(3.62±0.83)d and pharyngeal congestion elimination time(3.83±1.21)d in the observation group were lower than those in the control group,which were of statistically significances between both groups(P<0.05).Conclusion:The treatment of ambroxol combined with dopamine for children with upper respiratory tract infection can significantly improve the clinical efficacy,effectively reduce the inflammatory factors,shorten treatment time.
作者
何逾祥
HE Yuxian(Dept.of Pediatrics,the 1st People’s Hospital of Foshan,Foshan 528000,China)
出处
《华夏医学》
CAS
2019年第5期37-40,共4页
Acta Medicinae Sinica
关键词
氨溴索
多巴胺
上呼吸道感染
炎性因子
ambroxol
dopamine
upper respiratory tract infection
inflammatory factor
