摘要
子宫内膜异位症(EMS)是一种常见的妇科疾病,也是女性不孕的常见原因之一。EMS所致不孕受多种因素的影响,其中子宫内膜容受性下降导致胚胎着床障碍是EMS患者不孕的重要原因之一。本文从子宫内膜形态改变、容受性相关因子表达紊乱、非编码RNA表达异常等方面对EMS患者内膜容受性改变进行综述,旨在为EMS相关性不孕的治疗提供新思路。
Endometriosis(EMS)is a common disease in women of reproductive age and one of the causes of female infertility.Infertility in women caused by EMS is affected by many factors,among which the loss of endometrial receptivity leads to embryo implantation disorder is an important reason.This article reviews the endometrial receptivity changes in patients with EMS from the aspects of endometrial morphological changes,aberrant expression of receptivity-related factors,and abnormal expression of non-coding RNA.It aims at providing evidence for facilitating clinical therapy of EMS-related infertility.
作者
朱靓雯
薛晴
Zhu Jingwen;Xue Qing(Department of Gynecology and Obstetrics,Peking University First Hospital,Beijing 100034,China)
出处
《中华生殖与避孕杂志》
CAS
CSCD
北大核心
2020年第3期246-249,共4页
Chinese Journal of Reproduction and Contraception
基金
国家重点研发计划(2017YFC1001203)。