摘要
目的探讨潜伏期注射杜非合剂(盐酸哌替啶100 mg和盐酸异丙嗪25 mg混合注射液)镇痛对阴道分娩初产妇分娩结局的影响。方法选取我院2018年1月~2018年8月产房分娩记录中无内科合并症且经阴道分娩的足月初产妇90例,行回顾性分析。将潜伏期给予杜非合剂的产妇设为注射组(45例),将未使用杜非合剂的产妇设为对照组(45例),比较两组产程时长、产时及产后两小时阴道出血量、羊水粪染率及新生儿Apgar评分的差异。结果注射组第一产程和总产程长于对照组,差异有统计学意义(P<0.05)。注射组第二产程与对照组相比,差异无统计学意义(P>0.05)。注射组的羊水粪染率低于对照组(P<0.05),产后两小时阴道出血量和新生儿Apgar评分两组比较差异均无统计学意义(P>0.05)。结论阴道分娩初产妇在潜伏期使用杜非合剂镇痛是安全可靠的,虽存在第一产程时间延长,但产妇羊水粪染率小于未使用杜非合剂者,且对第二产程、产时及产后两小时阴道出血、新后儿Apgar评分无明显影响。
Objective To investigate the effect of preemptive injection of Dufei mixture(pethidine 100 mg and promethazine 25 mg)on the outcome of vaginal delivery.Methods 90 full-term primiparas without medical complications in the delivery records of our hospital from January 2018 to August 2018 were selected for retrospective analysis.The pregnant women were given Dufei mixture in the incubation period were divided into injection group(45 cases)and control group(45 cases)respectively.The differences of the duration of labor,the amount of vaginal bleeding,the rate of amniotic fluid fecal staining and the Apgar score of the newborn between the two groups were compared.Results The duration of first and total stage of labor of injection group were longer than that of control group,and the difference showed statistically significance.The fecal staining rate of amniotic fluid of injection group was lower than that of control group.Difference between the duration of second stage of labor,the amount of postpartum bleeding(in 2hrs),and newborn Apgar score of injection group and control group showed no statistically significance.Conclusion It is reliable and safe to employ pethidine hydrochloride and promethazine hydrochloride as the labor analgesic drug in the incubation.
作者
唐瑞
文娇
于霞
TANG Rui;WEN Jiao;YU Xia(Department of Obstetrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China)
出处
《西部医学》
2020年第5期684-686,共3页
Medical Journal of West China
