摘要
目的:评价选择性慧差引导经上皮准分子激光角膜切削术(selective coma-guided trans-epithelial photorefractive keratectomy,Corneal-WA TPRK)在矫正初始眼非对称角膜散光方面的临床疗效。方法:本研究为前瞻性随机对照研究。挑选术前角膜形态对称性不佳、角膜慧差>0.25μm的患者43例(84眼),随机分为选Corneal-WA TPRK组21例(41眼)和无消像差引导的经上皮准分子激光角膜切削术(AberrationFree TPRK)组22例(43眼)。对比两组术后1、3、6个月的裸眼视力,角膜慧差及术后6个月的对比敏感度。结果:术后1、3、6个月,两组裸眼视力比较差异无统计学意义(P>0.05)。术后1、3、6个月,Corneal-WA TPRK组角膜慧差均明显低于Aberration-Free TPRK组,差异均有统计学意义(P<0.05)。术后6个月,Corneal-WA TPRK组3、6、12 c/d空间频率对比敏感度均明显高于Aberration-Free TPRK组,差异均有统计学意义(P<0.05)。结论:Corneal-WA TPRK有较高的有效性、安全性和可预测性,术后角膜慧差更少,对比敏感度更好,能显著提升视觉质量。
Objective:To evaluate the clinical effect of selective coma-guided trans-epithelial photorefractive keratectomy(Corneal-WA TPRK)in correcting initial asymmetric corneal astigmatism.Method:This was a prospective randomized controlled study.Forty-three cases(84 eyes)with asymmetric corneal astigmatism and coma>0.25μm before operation were randomly assigned to the Corneal-WA TPRK group 21 cases(41 eyes)and the aberration-free transepithelial photorefractive keratectomy(Aberration-Free TPRK)group 22 cases(43 eyes).The uncorrected visual acuity and corneal coma at 1,3 and 6 months after operation and the contrast sensitivity at 6 months after operation of the two groups were compared.Result:At 1,3 and 6 months after operation,the uncorrected visual acuity of the two groups were compared,and the difference was not statistically significant(P>0.05).At 1,3 and 6 months after operation,the corneal coma in the Corneal-WA TPRK group were significantly lower than those of the Aberration-Free TPRK group,and the differences were statistically significant(P<0.05).At six months after operation,the contrast sensitivity of spatial frequencies in 3,6 and 12 c/d in the Corneal-WA TPRK group were significantly higher than those of the Aberration-Free TPRK group,and the differences were statistically significant(P<0.05).Conclusion:Corneal-WA TPRK has higher effectiveness,safety and predictability,less corneal coma,better contrast sensitivity and significantly improved visual quality.
作者
石志成
彭超
梁翠萍
吕顺欢
罗小柳
刘玉爱
SHI Zhicheng;PENG Chao;LIANG Cuiping;LYU Shunhuan;LUO Xiaoliu;LIU Yuai(Jiangmen Central Hospital,Jiangmen 529030,China)
出处
《中外医学研究》
2020年第12期6-9,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
江门市科技计划项目(项目编号:2017A4017)。
关键词
近视
散光
经上皮准分子激光角膜切削术
角膜波前像差
对比敏感度
Myopia
Astigmatism
Trans-epithelial photorefractive keratectomy
Corneal wavefront aberration
Contrast sensitivity
