摘要
目的分析对慢性再生障碍性贫血患者使用环孢素A联合康力龙的临床治疗效果。方法本次对照实验中于我院选取70例患者作为研究对象,经检查诊断后证实为慢性再生障碍性贫血,需接受治疗。据分析调查,患者资料真实,符合入组标准。采用随机数字法将70例患者随机分配为对照组和观察组,每组35例患者,并分别使用不同药物治疗,其中对照组使用康力龙治疗,观察组与之不同,需在康力龙的基础上增加环孢素A进行联合治疗,并由医护人员做好详细记录,在治疗后对比两种不同疗法的临床应用疗效。结果观察组治疗有效率高达(82.85%),对照组治疗有效率仅为(57.14%),观察组治疗有效率明显高于对照组,存在统计学意义(P<0.05)。其次,在对患者实施治疗前,其血红蛋白、中性粒细胞及血小板等血常规指标无较大差异,不存在统计学意义(P>0.05);治疗后,使用环孢素A联合康力龙治疗的观察组,其血常规指标明显更优于对照组(P<0.05)。结论对慢性再生障碍性贫血患者采取环孢素A、康力龙联合治疗可有效改善该病症所带来的临床症状,提高患者预后生活质量,应用价值较高。
Objective To analyze the clinical efficacy of cyclosporine a combined with Stanozolol in patients with chronic aplastic anemia.Methods A total of 70 patients in our hospital were selected as subjects in this control study.They were diagnosed as chronic aplastic anemia and needed to be treated.According to the analysis investigation,the patient data is true,conforms to the group admission standard.70 patients were randomly divided into control group and observation group,35 patients in each group were treated with different drugs,in which the control group was treated with Kanglilong,the observation group was different from the control group,cyclosporine a should be added to Stanozololol’s regimen for combination therapy,and detailed notes should be made by the medical staff to compare the clinical effects of the two different treatments after treatment.Results The effective rate of observation group was as high as(82.85%),while that of control group was only(57.14%).The effective rate of observation group was significantly higher than that of Control Group(P<0.05).Secondly,there was no significant difference in hemoglobin,neutrophil and platelet before treatment,and there was no statistical significance(P>0.05).After treatment,the observation group treated with Cyclosporine A and Stanozolol,the indexes of blood routine examination were significantly better than that of control group(P<0.05).Conclusion The combination therapy of cyclosporine a and Kanglilong can effectively improve the clinical symptoms and quality of life of patients with chronic aplastic anemia.
作者
李慧丽
LI Hui-li(Panjin Liao Oil Gem Flower Hospital,Panjin 124010,China)
出处
《中国医药指南》
2020年第14期117-118,共2页
Guide of China Medicine
