摘要
目的研究分析兰索拉唑治疗胃食管反流病的临床疗效观察。方法选取2018年1月~12月在我院接受治疗的56例胃食管反流病患者为研究样本,根据随机数表法将其分为研究组与对照组各28例,对照组患者接受奥美拉唑进行治疗,研究组患者接受兰索拉唑进行治疗,两组患者均连续用药治疗8周,比较两组患者的临床治疗效果以及治疗期间不良反应发生情况。结果研究组患者的治疗总有效率为92.86%(26/28),对照组为82.14%(23/28),组间数据对比差异有统计学意义(P<0.05);研究组患者的不良反应发生率为3.57%(1/28),对照组为14.29%(4/28),组间数据对比差异有统计学意义(P<0.05)。结论对胃食管反流病患者采用兰索拉唑进行治疗,具有较高的治疗总有效率与安全性,值得在临床进行广泛应用。
Objective To study and analyze the clinical efficacy of lansoprazole in the treatment of gastroesophageal reflux disease(GERD).Methods 56 patients with gastroesophageal reflux disease(GERD)who were treated in our hospital from January to December 2018 were selected and divided into study group(n=28)and control group(n=28)according to random table method.The patients in the control group were treated with omeprazole,and the patients in the control group were treated with omeprazole.The patients in the study group were treated with lansoprazole for 8 weeks.The clinical effects and adverse reactions were compared between the two groups.Results The total effective rate of the patients in the study group was 92.86%(26/28).The control group was 82.14%(23/28),and there was significant difference between the two groups(P<0.05).The incidence of adverse reactions was 3.57%(1/28)in the study group and 14.29%(4/28)in the control group(P<0.05).Conclusion Lansoprazole is effective and safe in the treatment of gastroesophageal reflux disease(GERD),which is worthy to be widely used in clinic.
作者
洪素洁
HONG Su-jie(Beizhen Second People's Hospital,Beizhen 121308,China)
出处
《中国医药指南》
2020年第13期77-78,共2页
Guide of China Medicine
关键词
兰索拉唑
胃食管反流病
临床疗效
Lansoprazole
Gastroesophageal reflux disease
Clinical efficacy
