摘要
近年来,越来越多的研究表明,肠道菌群参与了人类多种疾病的发生发展,包括慢性肝病,如非酒精性脂肪肝、慢性乙型肝炎、肝硬化等。中医学中“脾”的生理病理功能的现代生物学基础之一可能是肠道菌群及其代谢产物等产生的作用。系统阐述肠道菌群及其代谢产物在肝脏疾病发病机制中的作用,并结合中医理论中“肝脾相关”理论,提出中医药调节肠道菌群,为临床治疗慢性肝病提供新思路。
In recent years,more and more studies have shown that intestinal flora is involved in the occurrence and development of various human diseases,including chronic liver diseases,such as non-alcoholic fatty liver,chronic hepatitis B,and cirrhosis.One of the modern biological foundations of the physiopathological function of“spleen”in Chinese medicine may be the effects of intestinal flora and its metabolites.Systematically elaborate the role of intestinal flora and its metabolites in the pathogenesis of liver diseases.Combined with the theory of“liver and spleen related”in Chinese medicine theory,it is proposed that Chinese medicine regulate intestinal flora to provide new ideas for clinical treatment of chronic liver disease.
作者
陈越
陈兰玲
CHEN Yue;CHEN Lanling(Hunan University of Chinese Medicine,Hunan Changsha 410208,China;The First Affiliated Hospital of Hunan University of Chinese Medicine,Hunan Changsha 410208,China)
出处
《中医药临床杂志》
2020年第4期646-650,共5页
Clinical Journal of Traditional Chinese Medicine
关键词
肠道微生态
慢性肝病
肝脾相关
Intestinal microecology
Chronic liver disease
Liver and spleen correlation
