摘要
目的:探究丁苯酞联合依达拉奉对急性脑梗死患者神经功能及日常生活能力的影响。方法:选取68例急性脑梗死患者为研究对象,应用随机数字表法分为观察组与对照组各34例,对照组患者在常规治疗基础上给予依达拉奉治疗,观察组在对照组基础上给予丁苯酞治疗,对比两组患者神经功能缺损评分(NIHSS)、改良Barthel指数(MBI)和Fugl-Meyer运动功能评分(FMA)及不良反应发生率。结果:治疗后,观察组NIHSS评分低于对照组,差异有统计学意义(P<0.05);治疗后,观察组MBI及FMA评分均高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为5.88%,与对照组的14.71%比较,差异无统计学意义(P>0.05)。结论:丁苯酞联合联合依达拉奉治疗急性脑梗死患者的疗效较好,可减轻对患者神经功能的损伤,提高其日常生活活动能力。
Objective: To investigate effects of Butylphthalide combined with Edaravone on neurological function and daily life ability in patients with acute cerebral infarction. Methods: 68 patients with acute cerebral infarction were selected as the research objects, and were divided into observation group and control group by using the random number table method, 34 cases in each. The control group was treated with Edaravone on the basis of conventional treatment, while the observation group was treated with Butylphthalide on the basis of those of the control group. The neurological deficit score(NIHSS), modified Barthel index(MBI), Fugl-Meyer motor function score(FMA) and complication rate were compared between the two groups. Results: After the treatment, the NIHSS score of the observation group was lower than that of the control group, and the difference was statistically significant(P<0.05). After the treatment, the MBI and FMA scores of the observation group were higher than those in the control group, the differences were statistically significant(P<0.05). Further, the incidences of adverse reactions in the observation group and the control group were 5.88% and 14.71%, respectively, and the difference was not statistically significant(P>0.05). Conclusions: Butylphthalide combined with Edaravone has a better curative effect on the patients with acute cerebral infarction, which can reduce the damage to patients’ nerve function and improve their daily life activities.
作者
潘广
PAN Guang(Department of Neurology of Kaiyuan Dongyuan Rehabilitation Hospital,Tongxu 475400 Henan,China)
出处
《中国民康医学》
2020年第6期8-10,共3页
Medical Journal of Chinese People’s Health
关键词
急性脑梗死
丁苯酞
依达拉奉
神经功能
日常生活能力
Acute cerebral infarction
Butylphthalide
Edaravone
Neurological function
Daily living ability
