摘要
间苯三酚是一种平滑肌解痉药,可用于治疗各种急性痉挛性疼痛,由于妊娠20周以前的先兆流产目前除了孕激素外,没有其他药物可以选择,因此有学者把它当成子宫收缩抑制剂,用于治疗先兆流产,尤其是妊娠20周前出现的先兆流产,以期延长孕周,改善妊娠结局。国内多数研究表明,间苯三酚可有效抑制子宫收缩,治疗先兆流产及先兆早产。就疗效及安全性而言,间苯三酚较其他保胎治疗药物有一定优势,但间苯三酚并不属于保胎药物范畴,因此,其用于治疗先兆流产及先兆早产的可行性仍存在争议。本文就国内外关于间苯三酚作为保胎药物的使用现状、疗效以及安全性予以简要综述。
Phloroglucinol,an antispasmodic agent,is often used to relieve various acute spasmodic pain.At present,there is no medicine for the threatened miscarriage before 20 weeks of gestation except progesterone.Thus,some scholars regard phloroglucinol as a uterine contraction inhibitor in the treatment of threatened miscarriage,especially before 20 weeks,to extend gestational age and improve pregnancy outcome.Most domestic studies show that phloroglucinol can efficiently inhibit uterine contractions to treat threatened miscarriage and preterm birth.In terms of efficacy and safety,phloroglucinol has certain advantages over other tocolytic agents.However,phloroglucinol does not belong to the category of tocolytic agents.Therefore,the feasibility of phloroglucinol for tocolysis is still controversial.This article reviews the application,efficacy and safety of phloroglucinol for tocolysis.
出处
《妇产与遗传（电子版）》
2019年第4期57-60,共4页
Obstetrics-Gynecology and Genetics (Electronic Edition)
基金
南方医科大学南方医院院长基金(2017B012)
南方医科大学2018年度大学生创新训练项目(201812121133)。
关键词
间苯三酚
保胎治疗
治疗结果
Phloroglucinol
Tocolysis
Treatment outcome
