摘要
目的:观察柴胡疏肝散联合黛力新对改善尿毒症患者负性情绪和睡眠行为的临床疗效。方法:选取2018年3月至2019年6月漳州市中医院收治的抑郁症合并睡眠障碍的尿毒症患者80例作为研究对象,按照随机数字表法随机分为对照组和观察组,每组40例。2组患者均接受常规血液透析治疗,其中对照组加用治疗抑郁症常规药物,观察组采用柴胡疏肝散联合黛力新中西药结合治疗手段,4周为1个疗程。2个疗程后比较2组患者的抑郁自评量表(SDS)、焦虑自评量表(SAS)评分和匹兹堡睡眠质量指数(PSQI)。结果:1)2组患者疗程结束后,抑郁焦虑情况和睡眠质量均有改善,但观察组治疗后SDS评分、SAS评分均低于对照组,差异有统计学意义(P<0.05);2)2组患者治疗后PSQI指数均有所降低,但观察组低于对照组,2组患者间差异有统计学意义(P<0.05)。结论:柴胡疏肝散联合黛力新能更有效地改善尿毒症患者的负性情绪,提高患者的睡眠质量,值得在临床上进一步推广。
Objective:To observe the clinical efficacy of Caihushugansan joint Deanxit in the treatment of uremic patients with negative emotion and sleep behavior.Methods:A total of 80 cases uremic patients with negative emotion and sleep disorder were randomly divided into control groups and treament groups.Both of two groups were given Hemodialysis treatment,while the control group were applied with conventional medicine for negative emotion,and the treament group was given Caihushugansan joint Deanxit treament,4 weeks as a course.After two courses of treatment,SDS、SAS and PSQI were compared in two groups of patients.Results:The SDS score,SAS scoreand PSQI in treatment group were significantly decreased after two courses of treatment compared to the control group(P<0.05).Conclusion:Caihushugansan joint Deanxit treament can significantly improve the negative emotions and sleep quality.So it is worthwhile to be further extended in clinic.
作者
方镇福
叶书梅
林秀春
FANG Zhenfu;YE Shumei;LIN Xiuchun(Zhangzhou Hospital of traditional Chinese Medicine,Zhangzhou 363000,China)
出处
《世界睡眠医学杂志》
2020年第2期237-238,共2页
World Journal of Sleep Medicine
