摘要
大肠埃希氏菌是一种条件性致病菌,致病性的大肠埃希氏菌具有高度的传染性,会严重危害健康。快速准确地测定大肠埃希氏菌的污染来源对有效缩小疫情影响范围极有帮助,从而避免对人类健康和经济贸易造成重大损失。建立简便高效的分型方法是微生物溯源的关键,常见的大肠埃希氏菌分型方法可分为表型分型和分子分型,这些分型方法各有优劣,具有不同的适用范围。本文详细介绍了大肠埃希氏菌的分型方法,并对国内外大肠埃希氏菌分型的研究进展进行综述,为致病菌溯源方法的选择提供参考依据,对防御并控制致病菌引起的流行病传播具有重要的意义。
Escherichia coli is a conditional pathogenic bacteria.Pathogenic E.coli is highly contagious and threatens human health.Rapid determination of the contaminant source of E.coli can help effectively control epidemic,to protect human health and reduce economy loss.Simple and efficient tracing techniques and typing methods are key to trace the source of pathogen.Common typing methods of E.coli include phenotypic typing and molecular typing.These typing methods have their own advantages and limitations,and have different application scopes.In this paper,phenotypic typing and molecular typing methods and the research progress of E.coli typing are reviewed.It will provide reference for the selection of traceability methods for pathogenic bacteria,and have the great significance for the prevention and control of epidemic spread caused by pathogenic bacteria.
作者
黄涛
山珊
黄艳梅
刘道峰
刘成伟
黄运红
黄昭鸿
龙中儿
HUANG Tao;SHAN Shan;HUANG Yan-Mei;LIU Dao-Feng;LIU Cheng-Wei;HUANG Yun-Hong;HUANG Zhao-Hong;LONG Zhong-Er(College of Life Sciences,Jiangxi Normal University,Nanchang,Jiangxi 330022,China;Jiangxi YeLi Medical Device Co.Ltd.,Nanchang,Jiangxi 330008,China;Jiangxi Province Key Laboratory of Diagnosing and Tracing of Foodborne Disease,Jiangxi Province Centre for Disease Control and Prevention,Nanchang,Jiangxi 330029,China)
出处
《微生物学通报》
CAS
CSCD
北大核心
2020年第3期892-902,共11页
Microbiology China
基金
江西省重点研发计划(20192BBGL70053,20192BBG70069)
江西省重点实验室计划(20171BCD40021)
江西省卫健委科技计划(20196001)。
关键词
大肠埃希氏菌
表型分型方法
分子分型方法
溯源方法
Escherichia coli
Phenotypic typing method
Molecular typing method
Traceability methods
