摘要
目的探讨连续性血液净化对多器官功能障碍综合征患者凝血及免疫功能的影响。方法将我院收治的70例多器官功能障碍综合征患者随机分为常规组和连续组,各35例。常规组采用常规治疗,连续组采用连续性血液净化治疗。比较两组的治疗效果。结果连续组治疗总有效率高于常规组(P<0.05)。治疗后,两组APTT、PT均缩短,FIB、DD水平均降低,且连续组优于常规组(P<0.05)。治疗后,连续组IgA、IgG、IgM及CD4+均高于常规组,CD8+低于常规组(P<0.05)。结论给予多器官功能障碍综合征患者连续性血液净化治疗,可改善其凝血及免疫功能,促使疾病转归。
Objective To investigate the influence of continuous blood purification on coagulation and immunologic functions in patients with multiple organ dysfunction syndrome.Methods Seventy multiple organ dysfunction syndrome patients admitted in our hospital were randomly divided into routine group and continuous group,with 35 cases in each group.Conventional treatment was used in the routine group and continuous blood purification treatment was used in the continuous group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment of the continuous group was higher than that of the routine group(P<0.05).After treatment,APTT,PT shortened,the levels of FIB and DD decreased in both groups,and those in the continuous group were better than the routine group(P<0.05).After treatment,IgA,IgG,IgM and CD4+in the continuous group were higher than those in the routine group,and CD8+was lower than that in the routine group(P<0.05).Conclusion Continuous blood purification therapy for multiple organ dysfunction syndrome patients can improve the coagulation and immunologic functions,and promote the prognosis of the disease.
作者
邵志永
SHAO Zhi-yong(the People's Hospital of Yongcheng,Yongcheng 476600,China)
出处
《临床医学研究与实践》
2020年第13期43-44,共2页
Clinical Research and Practice
关键词
连续性血液净化
多器官功能障碍综合征
凝血功能
免疫功能
continuous blood purification
multiple organ dysfunction syndrome
coagulation function
immunologic function
