摘要
干燥综合征(SS)是一种以淋巴细胞增殖和进行性外分泌腺损伤为特征的慢性、系统性自身免疫病。在我国,SS的规范化诊断和治疗落后于其他常见的风湿性疾病,如类风湿关节炎和系统性红斑狼疮。中国医师协会干燥综合征协作组联合口腔科和眼科专家,在借鉴国内外诊治经验和指南的基础上,制定了《原发性干燥综合征诊疗规范》,旨在规范SS诊断中关键指标(如血清抗SSA抗体和唇腺病理学)的检测和解读、建议采用公认的疾病活动度指标评价疾病、规范局部和全身受累患者的合理诊治。
Sj?gren's syndrome is a chronic systemic autoimmune disease characterized by lymphocyte proliferation and progressive exocrine gland damage.In China,standardized diagnosis and treatment for Sj?gren's syndrome lags behind other common rheumatic diseases,such as rheumatoid arthritis and systemic lupus erythematosus.Based on the evidence and guidelines from China and other countries,Chinese Sj?gren's Syndrome Collaborative Research Group together with stomatologist and ophthalmologist developed Standardization of diagnosis and treatment of primary Sj?gren's syndrome.The purposes are:(1)to standardize the detection and interpretation of key indicators for the diagnosis of Sj?gren's syndrome,including serum anti SSA antibody and labial gland pathology;(2)to suggest using widely accepted disease activity index in evaluation of the disease;(3)to standardize rational management for Sj?gren's syndrome patients with topical and systemic diseases.
作者
张文
厉小梅
徐东
刘冬舟
徐健
赵福涛
赵岩
曾小峰
董怡
Zhang Wen;Li Xiaomei;Xu Dong;Liu Dongzhou;Xu Jian;Zhao Futao;Zhao Yan;Zeng Xiaofeng;Dong Yi(Department of Rheumatology,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,National Clinical Research Center for Dermatologic and Immunologic Diseases,Beijing 100730,China;Department of Rheumatology,Anhui Provincial Hospital,He Fei 230036,China;Department of Rheumatology,Shenzhen People′s Hospital,Shenzhen 518020,China;Department of Rheumatology,the First Affiliated Hospital of Kunming Medical University,Kunming 650032,China;Department of Rheumatology,Shanghai Ninth People′s Hospital,Shanghai 200011,China)
出处
《中华内科杂志》
CAS
CSCD
北大核心
2020年第4期269-276,共8页
Chinese Journal of Internal Medicine
基金
国家重点研发计划精准医学专项(2017YFC0907600,2017YFC0907601,2017YFC0907605)
中国医学科学院协同创新项目(2017-I2M-3-001)。
关键词
原发性干燥综合征
诊断
治疗
Primary Sjogren's syndrome
Diagnosis
Treatment
