摘要
目的观察急性心肌梗死患者经皮冠状动脉介入联合替格瑞洛对其炎性因子及心肌酶谱的影响。方法选取于2017年5月-2018年10月在安阳市第三人民医院收治的78例经皮冠状动脉介入治疗的急性心肌梗死患者作为研究对象,依随机数表法分为对照组与观察组,每组各39例。对照组使用氯吡格雷,观察组使用替格瑞洛,对比两组患者炎性因子水平及心肌酶谱指标。结果观察组患者治疗后TNF-α、IL-6、IFN-γ、LDH、CK、CK-MB水平均较对照组低,差异具有统计学意义(P<0.05)。结论急性心肌梗死患者经皮冠状动脉介入联合替格瑞洛治疗后,可降低炎性反应,减轻心肌损伤,效果显著。
Objective To observe the effect of percutaneous coronary intervention combined with tegrilol on inflammatory factors and myocardial zymogram in patients with acute myocardial infarction. Methods 78 patients with acute myocardial infarction treated by percutaneous coronary intervention from May,2018, 2017 to October were randomly divided into control group(n=39)and observation group(n=39). Clopidogrel was used in the control group and tegrilol in the observation group. The levels of inflammatory factors and myocardial zymogram were compared between the two groups. Results After treatment, TNF-α, IL-6,IFN-γ, LDH, CK and CK-MB were lower than that of control group, and the difference was statistically significant(P<0.05).Conclusion After percutaneous coronary intervention combined with ticagrelor in patients with acute myocardial infarction, the inflammatory response can be reduced and myocardial injury can be reduced The effect is significant.
作者
呼庆华
Hu Qing-hua(Department of Cardiology,Anyang Third People’s Hospital,Anyang,Henan,455000,China)
出处
《黑龙江医学》
2020年第4期488-490,共3页
Heilongjiang Medical Journal
关键词
急性心肌梗死
经皮冠状动脉介入
替格瑞洛
氯吡格雷
炎性因子
心肌酶谱
Acute myocardial infarction
Peradaneous Coronary intervention
Tegrilol
Clopidogrel
Inflammatory
Myocardial zymogram
