摘要
目的探讨急性ST段抬高型心肌梗死(STEMI)患者入院血清白蛋白水平与梗死相关动脉自发再灌注的关系。方法选取确诊为STEMI并在12 h内急诊行冠状动脉造影的患者207例。根据梗死相关动脉是否自发再灌注将患者分为非自发再灌注组(NSR组,n=122)和自发再通组(SR组,n=85)。采用logistic回归筛选梗死相关动脉自发再灌注的影响因素,采用ROC曲线评价入院血清白蛋白水平预测梗死相关动脉自发再灌注的价值。结果 SR组患者入院血清白蛋白水平高于NSR组(P<0.05)。Logistic回归分析结果显示,入院时血清白蛋白水平(OR=0.943,95%CI=0.878~0.992)是STEMI患者梗死相关动脉自发再灌注的独立影响因素。ROC曲线分析结果显示,入院血清白蛋白水平预测梗死相关动脉自发再灌注的曲线下面积为0.583(95%CI=0.504~0.661,P<0.05),截断值为41.95 g/L时,敏感度为56.6%,特异度为58.8%。结论入院血清白蛋白水平是STEMI患者梗死相关动脉自发再灌注的独立预测因素。
Objective To investigate the relationship between admission serum albumin level and spontaneous recanalization ofinfarct-related arteries in patients with acute ST segment elevation myocardial infarction(STEMI). Methods A total of 207 patientswho were diagnosed as STEMI and underwent emergent coronary angiography within 12 hours were selected, and allocated intonon-spontaneous recanalization group(NSR group, n=122) and spontaneous recanalization group(SR group, n=85)according tospontaneous recanalization of infarct-related arteries. Logistic regression analysis was used to screen the predictors of spontaneousrecanalization, and ROC curve was used to evaluate the value of admission serum albumin level for predicting spontaneous coro-nary recanalization. Results Admission serum albumin level in the SR group was significantly higher than that in the NSR group(P<0.05). Logistic regression analysis showed that admission serum albumin level(OR=0.934, 95% CI=0.878~0.992)were inde-pendent predictors of spontaneous recanalization of infarct-related arteries in STEMI patients. ROC curve results showed that thearea under ROC curve of admission serum albumin level predicting spontaneous recanalization of infarct-related arteries was 0.583(95% CI=0.504~0.661,P<0.05);when the cut-off value was 41.95 g/L, the sensitivity was 56.6%, and the specificity was 58.8%.Conclusion Admission serum albumin level is an independent predictor of spontaneous recanalization of infarct-related arteries inpatients with STEMI.
作者
关景
李林河
曾祥川
王忠
GUAN Jing;LI Lin-he;ZENG Xiang-chuan(Medical College of Shihezi University,Shihezi,Xinjiang,832002,China)
出处
《黑龙江医学》
2020年第3期293-296,共4页
Heilongjiang Medical Journal
关键词
急性ST段抬高型心肌梗死
梗死相关动脉
白蛋白
自发再灌注
Acute ST segment elevation myocardial infarction
Infarct-related artery
Albumin
Spontaneous recanalization
