摘要
目的探讨宫颈癌根治性放疗出现重度慢性放射性直肠炎的危险因素,并提出相应的护理干预措施。方法选取我院2017年1月至2019年3月收治的162例宫颈癌根治性放疗患者作为研究对象,其中治疗后出现重度慢性放射性直肠炎(SLRT)患者29例,未出现SLRT患者133例。采用我院设计的危险因素问卷调查表,对引发宫颈癌根治性放疗SLRT的相关因素和危险因素进行单因素和多因素logistic回归分析。结果临床分期、肿瘤大小及平均受照剂量是宫颈癌根治性放疗出现SLRT的危险因素(P<0.05),新辅助化疗是出现SLRT的保护因素(P<0.05),且放疗方式也是出现SLRT的独立因素(P<0.05)。结论宫颈癌根治性放疗出现SLRT与临床分期、肿瘤大小及平均受照剂量等密切相关,医护人员需采取适宜护理干预措施,合理选择放疗方式,尽量减少放射损伤,并辅以有效的化疗手段,提高患者生存率以及生活质量。
Objective To explore the risk factors of severe late rectal toxicity(SLRT)in radical radiotherapy of cervical cancer,and to put forward corresponding nursing intervention measures.Methods We selected 162 cases of patients undergoing radical radiotherapy for cervical cancer who were admitted to our hospital from January 2017 to March 2019 as the study objects,including 29 patients with SLRT after treatment and 133 patients without SLRT.The risk factors questionnaire designed by our hospital was used to carry out univariate and multivariate logistic regression analysis for the related factors and risk factors of SLRT for cervical cancer radical radiotherapy.Results The clinical stage,tumor size and average exposure dose were the risk factors for SLRT in radical radiotherapy for cervical cancer(P<0.05).The neoadjuvant chemotherapy was a protective factor for SLRT(P<0.05),and the type of radiotherapy was also an independent factor for SLRT(P<0.05).Conclusion The occurrence of SLRT in radical radiotherapy for cervical cancer was closely related to clinical stage,tumor size,and average exposure dose.So medical staff should take appropriate nursing interventions,choose radiation therapy reasonably,minimize radiation damage,and supplement with effective chemotherapy,Improve patient's survival rate and quality of life.
出处
《护理实践与研究》
2020年第8期30-32,共3页
Nursing Practice and Research
关键词
宫颈癌
根治性放疗
放射性直肠炎
危险因素
护理干预
Cervical cancer
Radical radiotherapy
Radiation proctitis
Risk factors
Nursing intervention
