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右美托咪啶在2型糖尿病患者全身麻醉中的应用及对血流动力学的影响

Application of Dexmedetomidine in General Anesthesia of Type 2 Diabetes Mellitus and its Effect on Hemodynamics
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摘要 目的探究2型糖尿病患者在全身麻醉中应用右美托咪啶的临床效果。方法选取湖南省人民医院2018年9月至2019年9月收治的行全身麻醉2型糖尿病患者74例为研究对象,按照手术时间的先后顺序分为对照组(n=37)与观察组(n=37)。对照组仅注射生理盐水,观察组在注射生理盐水的基础上加用右美托咪啶。结果与对照组相比,观察组在手术开始10 min、20 min后的心率与平均动脉压、血糖的数值波动均较小(P<0.05)。2组患者在手术开始10 min、20 min后的血氧饱和度比较,差异无统计学意义(P>0.05)。2组患者在不同时间段的舒张压、心率比较差异无统计学意义(P>0.05)。观察组在T1、T2时间段的收缩压与对照组相比差异有统计学意义(P<0.05)。结论2型糖尿病患者在全身麻醉中应用右美托咪啶的临床效果明显,可使患者在全身麻醉时得心率、平均动脉压等各项生命体征更加平稳,为手术的顺利进行起到积极作用。 Objective To investigate the clinical effect of dexmedetomidine in patients with type 2 diabetes under general anesthesia.Methods A total of 74 patients with type 2 diabetes treated with general anesthesia in hunan provincial people's hospital from September 2018 to September 2019 were selected as the study subjects and divided into the control group(n=37)and the observation group(n=37)according to the sequence of operation time.The control group was injected with normal saline only,and the observation group was injected with dexmedetomidine on the basis of normal saline.Results Compared with the control group,the fluctuation of heart rate,mean arterial pressure and blood glucose in the observation group after 10 min and 20 min after the operation was smaller(P<0.05).Compared with the blood oxygen saturation at 10 min and 20 min after surgery,the two groups had(P>0.05).There was no significant difference in DBP and HR between the two groups(P>0.05).Compared with the control group,the SBP of the observation group in T1 and T2 time period was significantly different(P<0.05).Conclusion The clinical effect of dexmedetomidine in general anesthesia in patients with type 2 diabetes is very significant.It can make the patient's heart rate,mean arterial pressure and other vital signs more stable during general anesthesia,which can promote the smooth operation.
作者 金曼 JIN Man(Hunan Provincial People's Hospital,Changsha,Hunan 410000,China)
机构地区 湖南省人民医院
出处 《大医生》 2019年第24期128-130,共3页 Doctor
关键词 2型糖尿病 麻醉 右美托咪啶 type 2 diabetes anesthesia dexmedetomidine
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