摘要
目的了解苏州市住院儿童肺炎的病原分布特点及流行特征。方法以2011年4月-2018年3月入住苏州大学附属儿童医院呼吸科的临床肺炎住院儿童为对象,采集鼻咽分泌物,对儿童肺炎常见的细菌和病毒病原进行检测。结果 4 765名临床肺炎病例中,病原检出阳性3 602例(75.6%),细菌检出阳性2 736例(57.4%),阳性率最高的为肺炎链球菌(Streptococcus pneumoniae,SP)(20.3%),其次为流感嗜血杆菌(Haemophilus influenzae,H.i)(15.5%);病毒检出阳性2 101例(44.1%),阳性率最高的为呼吸道合胞病毒(respiratory syncytial virus,RSV)(16.4%),其次为博卡病毒(bocavirus,BoV)(13.6%)。细菌和病毒混合感染1 235例(25.9%),最主要类型为呼吸道合胞病毒和肺炎链球菌、博卡病毒和草绿色链球菌(Streptococcus viride,SV)。结论 SP、H.i、RSV、BoV是临床肺炎最主要的病原,病原分布在月龄、季节上存在统计学差异,细菌和病毒混合感染率较高。
Objective To understand the distribution and epidemic characteristics of common pathogens of pneumonia among hospitalized children in Suzhou. Methods Nasopharyngeal secretions were collected from hospitalized children with clinical pneumonia admitted to the respiratory department of Children’s Hospital Affiliated to Suzhou University from April 2011 to March 2018 to detect common viral and bacterial pathogens of children’s pneumonia. Results The total positive rate of pathogens was 75.6% in the 4 765 clinical pneumonia cases. The positive rate of bacterial pathogens was 57.4%. Streptococcus pneumoniae(SP) was the highest, followed by Haemophilus influenzae(H.i);The positive rate of viral pathogens was 44.1%. Respiratory syncytial virus(RSV) was the highest, followed by Bocavirus(BoV). The mixed infection rate of bacteria and virus was 25.9%, and the most common types were RSV and SP, BoV and Streptococcus viride(SV). Conclusions SP, H.i, RSV and BoV are the main pathogens of clinical pneumonia in children. There are statistical differences in different age groups and seasons of hospitalized children’s pneumonia in Suzhou. The mixed infection rate of bacteria and virus is high.
作者
徐鑫鑫
陈立凌
田健美
诸俊
林玉尊
王胤
高君枚
邵雪君
张涛
张钧
赵根明
XU Xin-xin;CHEN Li-ling;TIAN Jian-mei;ZHU Jun;LIN Yu-zun;WANG Yin;GAO Jun-mei;SHAO Xue-jun;ZHANG Tao;ZHANG Jun;ZHAO Gen-ming(Department of Epidemiology,School of Public Health,Fudan University,Shanghai 200032,China;Department of Infectious Disease Prevention and Control,Suzhou Center for Disease Control and Prevention,Suzhou 215000,China;Children's Hospital Affiliated to Suzhou University,Suzhou 215003,China)
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2020年第3期264-268,共5页
Chinese Journal of Disease Control & Prevention
基金
中美新发和再发传染病合作项目(5U2GGH000018)
第四轮公共卫生三年行动计划重点学科建设项目(15GWZK0101)
苏州卫生和计划生育委员会民生科技关键技术(SS201870)。
关键词
住院儿童
临床肺炎
病原分布
Hospitalized children
Clinical pneumonia
Pathogenic distribution
