摘要
锌基可降解生物材料与已被广泛研究的生物可降解材料(镁和铁)相比,具有更合适的生物降解速率,因而近年来受到了广泛的研究和关注。然而,锌在模拟体液中的长期腐蚀降解行为尚不明确。本研究采用电化学腐蚀测试、表面化学成分分析及降解模式演变观察相结合的方法,系统研究了锌在林格氏液中浸泡56 d的腐蚀演化过程。根据电化学结果显示,锌的腐蚀速率Pi在浸泡过程中基本保持稳定,约为0.06~0.10 mm/a;失重法测定腐蚀速率为0.3mm/a到0.5mm/a。浸泡过程中生成的腐蚀产物主要为Zn5(CO3)2(OH)6和CaCO3,为较致密的细条花棒状和块状产物层,且随着浸泡时间延长逐渐累积。去除腐蚀产物后发现,样品表面出现较严重的局部腐蚀,且腐蚀沟槽的尺寸随浸泡时间的延长而增大,浸泡42d腐蚀沟槽宽约为10μm。本研究为锌基可降解生物材料后期表面改性及潜在生物医学应用提供了数据积累和研究基础。
In recent years, zinc-based biodegradable materials have gained significant attention due to their desirable biodegradation rate compared with other extensively explored biodegradable metals, such as magnesium and iron. However, the long-term corrosion behavior of zinc in simulated body fluid remain unclear. In this study, we performed a 56 d immersion test to reveal the long-term evolution of corrosion behavior of zinc in Ringer’s solution using electrochemical methods and surface analysis. The results showed that the corrosion rate of Zn calculated from current density ranged from 0.06 to 0.1 mm/a during the immersion. Its corrosion rate, determined by weight loss method, was from 0.3 mm/a to 0.5 mm/a. The corrosion products were mainly composed of Zn5(CO3)2(OH)6 and CaCO3. These products were firm, rod-and block-like formed on Zn surface, and gradually accumulated with increase of immersion time. Its surface morphology after removing corrosion products exhibited increasing sizes of corrosion pits and grooves with increase of immersion time. And width of the corrosion pits and grooves was about 10 μm after 42 d immersion. This study provides a guideline for the further surface modification and biomedical applications of Zn-based materials in terms of biodegradation profile.
作者
唐帅
张文泰
钱军余
鲜鹏
莫小山
黄楠
万国江
TANG Shuai;ZHANG Wentai;QIAN Junyu;XIAN Peng;MO Xiaoshan;HUANG Nan;WAN Guojiang(Key Laboratory of Advanced Technologies of Materials,Ministry of Education,School of Materials Science and Engineering,Southwest Jiaotong University,Chengdu 610031,China)
出处
《无机材料学报》
SCIE
EI
CAS
CSCD
北大核心
2020年第4期461-468,共8页
Journal of Inorganic Materials
基金
国家重点研发计划(2016YFC1102500)
国家自然科学基金(21473138)。
关键词
可降解锌
长期腐蚀行为
电化学测试
表面化学
biodegradable zinc
long-term corrosion behavior
electrochemical test
surface chemistry
